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BIOMARKER:

NPM1 mutation + FLT3-TKD mutation

i
Entrez ID:
4years
NPM1 and FLT3-TKD mutations are enriched in patients with leukemia cutis. (PubMed, Dermatol Online J)
Our original hypothesis was that patients with LC would display a distinct mutation profile. Ultimately, the distribution of mutations observed in our cohort of LC patients largely reflects the mutational profile seen in AML patients in general.
Clinical • Journal
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FLT3 (Fms-related tyrosine kinase 3) • NPM1 (Nucleophosmin 1)
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NPM1 mutation • FLT3-TKD mutation • NPM1 mutation + FLT3-TKD mutation