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BIOMARKER:
NPM1 mutation + FLT3-TKD mutation
i
Other names:
Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin), Testicular Tissue Protein Li 128, Nucleolar Protein NO38, Numatrin, NPM1, Nucleophosmin 1, Nucleophosmin/Nucleoplasmin Family, Member 1, Nucleolar Phosphoprotein B23, FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
;
4869
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FLT3 overexpression (3)
FLT3 expression (2)
FLT3-ITD expression (2)
NPM1 expression (2)
CCDC86 expression + NPM1 expression (1)
FLT3 overexpression (3)
FLT3 expression (2)
FLT3-ITD expression (2)
NPM1 expression (2)
CCDC86 expression + NPM1 expression (1)
›
Associations
(1)
News
Trials
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Latest
4years
NPM1 and FLT3-TKD mutations are enriched in patients with leukemia cutis. (PubMed, Dermatol Online J)
Our original hypothesis was that patients with LC would display a distinct mutation profile. Ultimately, the distribution of mutations observed in our cohort of LC patients largely reflects the mutational profile seen in AML patients in general.
4 years ago
Clinical • Journal
|
FLT3 (Fms-related tyrosine kinase 3) • NPM1 (Nucleophosmin 1)
|
NPM1 mutation • FLT3-TKD mutation • NPM1 mutation + FLT3-TKD mutation
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