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BIOMARKER:

NF1 underexpression

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Entrez ID:

Related biomarkers:

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NF1 mutation (24)

BRAF mutation + NF1 mutation (2)

EGFR mutation + TP53 mutation + NF1 mutation (2)

IDH1 wild-type + NF1 mutation (2)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)

NF1 2195G>T (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

NF1 rearrangement (1)

NF1 mutation (1)

SDHB mutation + NF1 mutation (1)

NF1 7806+2T>C (0)

NF1 L581Ffs*6 (0)

NF1 mutation (24)

BRAF mutation + NF1 mutation (2)

EGFR mutation + TP53 mutation + NF1 mutation (2)

IDH1 wild-type + NF1 mutation (2)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)

NF1 2195G>T (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

NF1 rearrangement (1)

NF1 mutation (1)

SDHB mutation + NF1 mutation (1)

NF1 7806+2T>C (0)

NF1 L581Ffs*6 (0)

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2ms

NFS1 inhibits ferroptosis in gastric cancer by regulating the STAT3 pathway. (PubMed, J Bioenerg Biomembr)

NFS1 inhibits ferroptosis by activating the STAT3 pathway in GC cells. These results suggest that NFS1 may be a potential prognostic biomarker and therapeutic target to treat GC.

2 months ago

Journal

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NF1 (Neurofibromin 1) • GPX4 (Glutathione Peroxidase 4) • SLC7A11 (Solute Carrier Family 7 Member 11)

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GPX4 expression • NF1 underexpression