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    BIOMARKER:

    MYB underexpression

    i
    Other names: MYB, MYB Proto-Oncogene, Transcription Factor, V-Myb Avian Myeloblastosis Viral Oncogene Homolog, Transcriptional Activator Myb, Proto-Oncogene C-Myb, Oncogene AMV, C-Myb_CDS, C-Myb, Cmyb
    Entrez ID:
    4602
    Related biomarkers:
    Fusion
    Others
    almost3years
    MYB interacts with androgen receptor, sustains its ligand-independent activation and promotes castration resistance in prostate cancer. (PubMed, Br J Cancer)
    Our findings reveal a novel MYB-AR crosstalk in PCa and establish its role in castration resistance.
    Journal
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    AR (Androgen receptor) • MYB (MYB Proto-Oncogene, Transcription Factor) • KLK3 (Kallikrein-related peptidase 3)
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    MYB underexpression