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BIOMARKER:
KIT V559A
i
Other names:
KIT, KIT proto-oncogene receptor tyrosine kinase, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
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Entrez ID:
3815
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
Chr t(8;21) + KIT mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation + CSF3R mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation (3)
KIT P577del + KIT W557Lfs*5 + KIT Y823D (2)
Chr inv(16)t(16;16) + KIT mutation (1)
KIT wild-type + SDHB deletion (1)
RUNX1-RUNX1T1 fusion + KIT D816 (1)
Chr t(8;21) + KIT mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation + CSF3R mutation (4)
Chr t(8;21)(q22;q22) + RUNX1-RUNX1T1 fusion + KIT exon 17 mutation (3)
KIT P577del + KIT W557Lfs*5 + KIT Y823D (2)
Chr inv(16)t(16;16) + KIT mutation (1)
KIT wild-type + SDHB deletion (1)
RUNX1-RUNX1T1 fusion + KIT D816 (1)
›
Associations
News
Trials
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Latest
27d
Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial (clinicaltrials.gov)
P2, N=40, Active, not recruiting, National Cancer Institute (NCI) | Suspended --> Active, not recruiting
27 days ago
Enrollment closed
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA D842V • KIT L576P • KIT K642E • KIT V559 • KIT V559A • KIT W557
|
paclitaxel • Tasigna (nilotinib)
11ms
Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial (clinicaltrials.gov)
P2, N=40, Suspended, National Cancer Institute (NCI) | Recruiting --> Suspended
11 months ago
Trial suspension
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA D842V • KIT L576P • KIT K642E • KIT V559 • KIT V559A • KIT W557
|
paclitaxel • Tasigna (nilotinib)
over1year
Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial (clinicaltrials.gov)
P2, N=40, Recruiting, National Cancer Institute (NCI) | Initiation date: Sep 2023 --> Dec 2023
over 1 year ago
Trial initiation date
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA D842V • KIT L576P • KIT K642E • KIT V559 • KIT V559A • KIT W557
|
paclitaxel • Tasigna (nilotinib)
over1year
Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial (clinicaltrials.gov)
P2, N=40, Recruiting, National Cancer Institute (NCI) | Not yet recruiting --> Recruiting
over 1 year ago
Enrollment open
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA D842V • KIT L576P • KIT K642E • KIT V559 • KIT V559A • KIT W557
|
paclitaxel • Tasigna (nilotinib)
over1year
Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial (clinicaltrials.gov)
P2, N=40, Recruiting, National Cancer Institute (NCI) | Initiation date: Jun 2023 --> Sep 2023
over 1 year ago
Trial initiation date
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA D842V • KIT L576P • KIT K642E • KIT V559 • KIT V559A • KIT W557
|
paclitaxel • Tasigna (nilotinib)
over1year
Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial (clinicaltrials.gov)
P2, N=40, Recruiting, National Cancer Institute (NCI) | Not yet recruiting --> Recruiting | Initiation date: Dec 2022 --> Jun 2023
over 1 year ago
Enrollment open • Trial initiation date
|
PDGFRA (Platelet Derived Growth Factor Receptor Alpha)
|
PDGFRA D842V • KIT L576P • KIT K642E • KIT V559 • KIT V559A • KIT W557
|
paclitaxel • Tasigna (nilotinib)
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