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BIOMARKER:

Chr t(8;21) + KIT mutation

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Other names: KIT, KIT proto-oncogene receptor tyrosine kinase, C-Kit, CD117, PBT, SCFR, Stem Cell Factor Receptor, V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Entrez ID:
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Trials
Chr t(8;21) + KIT mutation
AML
venetoclax + midostaurin
Sensitive: C3 – Early Trials
Chr t(8;21) + KIT mutation
AML
venetoclax
Resistant: C3 – Early Trials
Chr t(8;21) + KIT mutation
AML
cabozantinib tablet
Sensitive: D – Preclinical