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DRUG:

INV322

i
Other names: INV322
Associations
Trials
Company:
Invenra
Drug class:
CTLA4 inhibitor, CD25 inhibitor
Associations
Trials
2years
INV322, a TME selective CD25 x CTLA4 bispecific antibody approach for depletion of tumor restricted Tregs (SITC 2022)
IND-enabling activities are underway with INV322. Ethics Approval All animal studies were reviewed and approved under Invenra's IACUC protocol (I-RP-A-07).
PD(L)-1 Biomarker • IO biomarker
|
CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4) • IL2RA (Interleukin 2 receptor, alpha)
|
CTLA4 expression
|
INV322