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DRUG:
Imjudo (tremelimumab-actl)
i
Other names:
CP-675206, CP-675,206, CP-675, PF-06753388, CP 675, CP675, PF 06753388, PF06753388, CP675206, CP 675206
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News alerts, weekly reports and conference planners
Associations
(60)
News
Trials
Company:
AstraZeneca, Pfizer
Drug class:
CTLA4 inhibitor
Related drugs:
‹
ipilimumab (223)
KN046 (19)
cadonilimab (10)
iparomlimab/tuvonralimab (3)
ipilimumab biosimilar (CS1002) (2)
MK-1308 (2)
GI-101 (1)
BNT316 (1)
XTX101 (1)
MEDI5752 (1)
XmAb717 (1)
AI-061 (0)
ATOR-1015 (0)
BMS-986218 (0)
BMS-986249 (0)
BMS-986288 (0)
BT-001 (0)
CD200AR-L (0)
CTLA4 inhibitor (0)
IBI310 (ipilimumab biosimilar) (0)
INV322 (0)
KD6001 (0)
MT-8421 (0)
prolgolimab/nurulimab (0)
ONCR-177 (0)
PF-06753512 (0)
RP2 (0)
RP3 (0)
SAL008 (0)
SYN-27M (0)
TG6050 (0)
YH001 (0)
XmAb22841 (0)
SI-B003 (0)
MGD019 (0)
ADG126 (0)
HBM4003 (0)
MK-1308A (0)
ipilimumab (223)
KN046 (19)
cadonilimab (10)
iparomlimab/tuvonralimab (3)
ipilimumab biosimilar (CS1002) (2)
MK-1308 (2)
GI-101 (1)
BNT316 (1)
XTX101 (1)
MEDI5752 (1)
XmAb717 (1)
AI-061 (0)
ATOR-1015 (0)
BMS-986218 (0)
BMS-986249 (0)
BMS-986288 (0)
BT-001 (0)
CD200AR-L (0)
CTLA4 inhibitor (0)
IBI310 (ipilimumab biosimilar) (0)
INV322 (0)
KD6001 (0)
MT-8421 (0)
prolgolimab/nurulimab (0)
ONCR-177 (0)
PF-06753512 (0)
RP2 (0)
RP3 (0)
SAL008 (0)
SYN-27M (0)
TG6050 (0)
YH001 (0)
XmAb22841 (0)
SI-B003 (0)
MGD019 (0)
ADG126 (0)
HBM4003 (0)
MK-1308A (0)
›
Associations
(60)
News
Trials
VERI cancer hierarchy
Reset Filters
No biomarker
Non Small Cell Lung Cancer
No biomarker
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: A1 - Approval
durvalumab + tremelimumab-actl
Sensitive
:
A1
durvalumab + tremelimumab-actl
Sensitive: A1 - Approval
durvalumab + tremelimumab-actl
Sensitive
:
A1
No biomarker
Hepatocellular Cancer
No biomarker
Hepatocellular Cancer
durvalumab + tremelimumab-actl
Sensitive: A1 - Approval
durvalumab + tremelimumab-actl
Sensitive
:
A1
durvalumab + tremelimumab-actl
Sensitive: A1 - Approval
durvalumab + tremelimumab-actl
Sensitive
:
A1
PD-L1 expression
Lung Non-Small Cell Squamous Cancer
PD-L1 expression
Lung Non-Small Cell Squamous Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
PD-L1 expression
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 expression
Lung Non-Squamous Non-Small Cell Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
PD-L1 overexpression
Lung Non-Small Cell Squamous Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 overexpression
Lung Non-Squamous Non-Small Cell Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
No biomarker
Lung Adenocarcinoma
No biomarker
Lung Adenocarcinoma
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
No biomarker
Lung Non-Small Cell Squamous Cancer
No biomarker
Lung Non-Small Cell Squamous Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
MSI-H/dMMR
Gastroesophageal Junction Adenocarcinoma
MSI-H/dMMR
Gastroesophageal Junction Adenocarcinoma
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
MSI-H/dMMR
Gastric Cancer
MSI-H/dMMR
Gastric Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
MSI-H/dMMR
Esophageal Cancer
MSI-H/dMMR
Esophageal Cancer
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
durvalumab + tremelimumab-actl
Sensitive: A2 - Guideline
durvalumab + tremelimumab-actl
Sensitive
:
A2
TMB-H
Urothelial Cancer
TMB-H
Urothelial Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
ARID1A mutation
Non Small Cell Lung Cancer
ARID1A mutation
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
TMB-H
Non Small Cell Lung Cancer
TMB-H
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
PD-L1 expression
Non Small Cell Lung Cancer
PD-L1 expression
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
TMB-H
Squamous Cell Carcinoma of Head and Neck
TMB-H
Squamous Cell Carcinoma of Head and Neck
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
KMT2D mutation
Squamous Cell Carcinoma of Head and Neck
KMT2D mutation
Squamous Cell Carcinoma of Head and Neck
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
PD-L1 overexpression
Squamous Cell Carcinoma of Head and Neck
PD-L1 overexpression
Squamous Cell Carcinoma of Head and Neck
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
ATM mutation
Squamous Cell Carcinoma of Head and Neck
ATM mutation
Squamous Cell Carcinoma of Head and Neck
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
STK11 mutation
Lung Non-Squamous Non-Small Cell Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
PD-L1 underexpression
Non Small Cell Lung Cancer
PD-L1 underexpression
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
HLA-DQB1*03:01
Small Cell Lung Cancer
HLA-DQB1*03:01
Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
EGFR wild-type
Non Small Cell Lung Cancer
EGFR wild-type
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
ALK wild-type
Non Small Cell Lung Cancer
ALK wild-type
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
KRAS mutation
Non Small Cell Lung Cancer
KRAS mutation
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
KEAP1 mutation
Non Small Cell Lung Cancer
KEAP1 mutation
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
STK11 mutation
Non Small Cell Lung Cancer
STK11 mutation
Non Small Cell Lung Cancer
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
durvalumab + tremelimumab-actl
Sensitive: B - Late Trials
durvalumab + tremelimumab-actl
Sensitive
:
B
BRCA1 mutation
Ovarian Cancer
BRCA1 mutation
Ovarian Cancer
olaparib + tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
olaparib + tremelimumab-actl
Sensitive
:
C2
olaparib + tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
olaparib + tremelimumab-actl
Sensitive
:
C2
BRCA2 mutation
Ovarian Cancer
BRCA2 mutation
Ovarian Cancer
olaparib + tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
olaparib + tremelimumab-actl
Sensitive
:
C2
olaparib + tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
olaparib + tremelimumab-actl
Sensitive
:
C2
PD-L1 expression
Squamous Cell Carcinoma of Head and Neck
PD-L1 expression
Squamous Cell Carcinoma of Head and Neck
durvalumab + tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
durvalumab + tremelimumab-actl
Sensitive
:
C2
durvalumab + tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
durvalumab + tremelimumab-actl
Sensitive
:
C2
MLH1 mutation
Gastric Cancer
MLH1 mutation
Gastric Cancer
tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
tremelimumab-actl
Sensitive
:
C2
tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
tremelimumab-actl
Sensitive
:
C2
MLH3 mutation
Gastric Cancer
MLH3 mutation
Gastric Cancer
tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
tremelimumab-actl
Sensitive
:
C2
tremelimumab-actl
Sensitive: C2 – Inclusion Criteria
tremelimumab-actl
Sensitive
:
C2
^
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