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    DRUG:

    IMU-201

    i
    Other names: IMU-201, PD1-Vaxx, APi2568, IMU 201, IMU201
    Company:
    Imugene
    Drug class:
    PD1 inhibitor
    Related drugs:
    1m
    Neo-POLEM: A Phase II Trial of Neoadjuvant PD-1 Vaccine PD1-Vaxx in Operable MSI High Colorectal Cancer (clinicaltrials.gov)
    P2, N=44, Not yet recruiting, University of Southampton
    New P2 trial
    |
    PD-1 (Programmed cell death 1)
    |
    IMU-201
    1m
    IMPRINTER: A Study of IMU-201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults with Non-Small Cell Lung Cancer (clinicaltrials.gov)
    P1, N=24, Active, not recruiting, Imugene Limited | Trial completion date: Mar 2026 --> May 2025 | Trial primary completion date: Feb 2026 --> Nov 2024
    Trial completion date • Trial primary completion date • Combination therapy
    |
    PD-L1 (Programmed death ligand 1) • PD-1 (Programmed cell death 1)
    |
    PD-L1 expression
    |
    PD-L1 IHC 22C3 pharmDx • VENTANA PD-L1 (SP263) Assay • VENTANA PD-L1 (SP142) Assay
    |
    Tecentriq (atezolizumab) • IMU-201
    11ms
    IMPRINTER: A Study of IMU-201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults With Non-Small Cell Lung Cancer (clinicaltrials.gov)
    P1; Recruiting --> Active, not recruiting | N=88 --> 24
    Combination therapy • Enrollment change • Enrollment closed
    |
    PD-L1 (Programmed death ligand 1) • PD-1 (Programmed cell death 1)
    |
    PD-L1 expression
    |
    PD-L1 IHC 22C3 pharmDx • VENTANA PD-L1 (SP263) Assay • VENTANA PD-L1 (SP142) Assay
    |
    Tecentriq (atezolizumab) • IMU-201
    over1year
    IMPRINTER: A Study of IMU-201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults With Non-Small Cell Lung Cancer (clinicaltrials.gov)
    P1; N=22 --> 88 | Trial completion date: Jul 2023 --> Mar 2026 | Trial primary completion date: Dec 2022 --> Feb 2026
    Combination therapy • Trial completion date • Trial primary completion date • Enrollment change
    |
    PD-L1 (Programmed death ligand 1) • PD-1 (Programmed cell death 1)
    |
    PD-L1 expression
    |
    PD-L1 IHC 22C3 pharmDx • VENTANA PD-L1 (SP263) Assay • VENTANA PD-L1 (SP142) Assay
    |
    Tecentriq (atezolizumab) • IMU-201