Contact us to learn more about

our Premium Content: News alerts, weekly reports and conference planners

BIOMARKER:

HER-2 negative + HR negative + PD-L1 expression

Contact us to learn more about our Premium Content:

News alerts, weekly reports and conference planners

Entrez ID:

Related biomarkers:

‹

PD-L1 expression (356)

HER-2 positive (332)

PD-L1 overexpression (181)

HER-2 overexpression (132)

HER-2 negative (120)

HER-2 expression (87)

PD-L1 underexpression (46)

HER-2 underexpression (38)

PD-L1 negative (28)

HER-2 negative + PD-L1 expression (12)

HR positive + HER-2 negative (5)

HER-2 positive + PD-L1 expression (3)

CD47 positive + HER-2 positive (2)

CLDN18.2 expression + HER-2 negative (2)

CLDN18.2 positive + HER-2 negative (2)

EGFR overexpression + HER-2 overexpression (2)

ER positive + HER-2 negative (2)

FGFR2b overexpression + HER-2 negative (2)

HR positive + HER-2 underexpression (2)

PD-L1 expression + HER-2 overexpression (2)

HR negative + PD-L1 expression (2)

MSLN overexpression + PD-L1 overexpression (2)

PD-L1 expression + CD68 positive (2)

PD-L1 expression + PVR expression (2)

PD-L1 overexpression + CD8 overexpression (2)

TTF1 expression + PD-L1 expression (2)

miR-625-5p underexpression + PD-L1 overexpression (2)

CEACAM6 positive + HER-2 positive (1)

EGFR expression + HER-2 expression (1)

ER negative + HER-2 negative (1)

ER positive + PGR negative + HER-2 negative (1)

HER-2 positive + CAV1 overexpression (1)

HER-2 underexpression + ER underexpression (1)

HR positive + HER-2 positive (1)

MET expression + HER-2 expression (1)

MET overexpression + HER-2 overexpression (1)

TPBG underexpression + HER-2 overexpression (1)

TROP2 expression + HER-2 underexpression (1)

AXL overexpression + PD-L1 expression (1)

CGAS overexpression + PD-L1 overexpression (1)

CMTM4 expression + PD-L1 expression (1)

CMTM6 expression + PD-L1 expression (1)

CMTM6 overexpression + PD-L1 overexpression (1)

CXCL12 expression + PD-L1 underexpression (1)

HLA-A underexpression + PD-L1 expression (1)

HR positive + PD-L1 expression (1)

IGFBP2 overexpression + PD-L1 overexpression (1)

MHC-II overexpression + PD-L1 negative (1)

MHC-II overexpression + PD-L1 underexpression (1)

NKX2-1 expression + PD-L1 expression (1)

NR1H4 overexpression + PD‑L1 underexpression (1)

NT5E overexpression + PD-L1 expression (1)

PD-1 underexpression + PD-L1 overexpression (1)

PD-L1 expression + CD14 positive (1)

PD-L1 expression + CD47 expression (1)

PD-L1 expression + CD8 negative + GZMB negative (1)

PD-L1 expression + CD8 positive (1)

PD-L1 expression + CTLA4 expression (1)

PD-L1 expression + MTOR overexpression (1)

PD-L1 expression + REV3L overexpression (1)

PD-L1 overexpression + APOBEC3B overexpression (1)

PD-L1 overexpression + CCL5 overexpression (1)

PD-L1 overexpression + CD163 underexpression (1)

PD-L1 overexpression + ER positive (1)

PD-L1 overexpression + GZMA overexpression (1)

PD-L1 overexpression + LAG3 expression + CTAG1B expression (1)

PD-L1 overexpression + PD-L2 underexpression (1)

PD-L1 overexpression + SOX2 overexpression (1)

RBM17 expression + PD-L1 expression (1)

RET positive + PD-L1 overexpression (1)

SNX20 overexpression + PD-L1 overexpression (1)

STK11 underexpression + PD-L1 overexpression (1)

TFRC overexpression + PD-L1 underexpression (1)

TNFSF4 overexpression + PD-L1 overexpression (1)

TTF1 expression + PD-L1 overexpression (1)

ER negative + HER-2 positive (0)

ER positive + HER-2 positive (0)

ER positive + PGR positive + HER-2 positive (0)

HER-2 amplification + HR-positive (0)

HER-2 negative + AR positive + ER positive (0)

HER-2 negative + CLDN18.2 positive (0)

HER-2 negative + ER positive (0)

HER-2 negative + FGFR2b overexpression (0)

HER-2 negative + HR negative (0)

HER-2 negative + PGR positive (0)

HER-2 overexpression + HR negative (0)

HER-2 overexpression + HR positive (0)

HER-2 positive + HER-2 overexpression (0)

HER-2 positive + HR negative (0)

HER-2 positive + RAS wild-type (0)

HR negative + HER-2 positive (0)

PD-L1 expression + HER-2 expression (0)

PGR positive + HER-2 positive (0)

PD-L1 expression + LAG3 expression (0)

PD-L1 expression + TTF1 expression (0)

TMB + PD-L1 expression (0)

PD-L1 expression (356)

HER-2 positive (332)

PD-L1 overexpression (181)

HER-2 overexpression (132)

HER-2 negative (120)

HER-2 expression (87)

PD-L1 underexpression (46)

HER-2 underexpression (38)

PD-L1 negative (28)

HER-2 negative + PD-L1 expression (12)

HR positive + HER-2 negative (5)

HER-2 positive + PD-L1 expression (3)

CD47 positive + HER-2 positive (2)

CLDN18.2 expression + HER-2 negative (2)

CLDN18.2 positive + HER-2 negative (2)

EGFR overexpression + HER-2 overexpression (2)

ER positive + HER-2 negative (2)

FGFR2b overexpression + HER-2 negative (2)

HR positive + HER-2 underexpression (2)

PD-L1 expression + HER-2 overexpression (2)

HR negative + PD-L1 expression (2)

MSLN overexpression + PD-L1 overexpression (2)

PD-L1 expression + CD68 positive (2)

PD-L1 expression + PVR expression (2)

PD-L1 overexpression + CD8 overexpression (2)

TTF1 expression + PD-L1 expression (2)

miR-625-5p underexpression + PD-L1 overexpression (2)

CEACAM6 positive + HER-2 positive (1)

EGFR expression + HER-2 expression (1)

ER negative + HER-2 negative (1)

ER positive + PGR negative + HER-2 negative (1)

HER-2 positive + CAV1 overexpression (1)

HER-2 underexpression + ER underexpression (1)

HR positive + HER-2 positive (1)

MET expression + HER-2 expression (1)

MET overexpression + HER-2 overexpression (1)

TPBG underexpression + HER-2 overexpression (1)

TROP2 expression + HER-2 underexpression (1)

AXL overexpression + PD-L1 expression (1)

CGAS overexpression + PD-L1 overexpression (1)

CMTM4 expression + PD-L1 expression (1)

CMTM6 expression + PD-L1 expression (1)

CMTM6 overexpression + PD-L1 overexpression (1)

CXCL12 expression + PD-L1 underexpression (1)

HLA-A underexpression + PD-L1 expression (1)

HR positive + PD-L1 expression (1)

IGFBP2 overexpression + PD-L1 overexpression (1)

MHC-II overexpression + PD-L1 negative (1)

MHC-II overexpression + PD-L1 underexpression (1)

NKX2-1 expression + PD-L1 expression (1)

NR1H4 overexpression + PD‑L1 underexpression (1)

NT5E overexpression + PD-L1 expression (1)

PD-1 underexpression + PD-L1 overexpression (1)

PD-L1 expression + CD14 positive (1)

PD-L1 expression + CD47 expression (1)

PD-L1 expression + CD8 negative + GZMB negative (1)

PD-L1 expression + CD8 positive (1)

PD-L1 expression + CTLA4 expression (1)

PD-L1 expression + MTOR overexpression (1)

PD-L1 expression + REV3L overexpression (1)

PD-L1 overexpression + APOBEC3B overexpression (1)

PD-L1 overexpression + CCL5 overexpression (1)

PD-L1 overexpression + CD163 underexpression (1)

PD-L1 overexpression + ER positive (1)

PD-L1 overexpression + GZMA overexpression (1)

PD-L1 overexpression + LAG3 expression + CTAG1B expression (1)

PD-L1 overexpression + PD-L2 underexpression (1)

PD-L1 overexpression + SOX2 overexpression (1)

RBM17 expression + PD-L1 expression (1)

RET positive + PD-L1 overexpression (1)

SNX20 overexpression + PD-L1 overexpression (1)

STK11 underexpression + PD-L1 overexpression (1)

TFRC overexpression + PD-L1 underexpression (1)

TNFSF4 overexpression + PD-L1 overexpression (1)

TTF1 expression + PD-L1 overexpression (1)

ER negative + HER-2 positive (0)

ER positive + HER-2 positive (0)

ER positive + PGR positive + HER-2 positive (0)

HER-2 amplification + HR-positive (0)

HER-2 negative + AR positive + ER positive (0)

HER-2 negative + CLDN18.2 positive (0)

HER-2 negative + ER positive (0)

HER-2 negative + FGFR2b overexpression (0)

HER-2 negative + HR negative (0)

HER-2 negative + PGR positive (0)

HER-2 overexpression + HR negative (0)

HER-2 overexpression + HR positive (0)

HER-2 positive + HER-2 overexpression (0)

HER-2 positive + HR negative (0)

HER-2 positive + RAS wild-type (0)

HR negative + HER-2 positive (0)

PD-L1 expression + HER-2 expression (0)

PGR positive + HER-2 positive (0)

PD-L1 expression + LAG3 expression (0)

PD-L1 expression + TTF1 expression (0)

TMB + PD-L1 expression (0)

›

1m

The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets. (PubMed, Curr Cancer Drug Targets)

The expression of the PD-L1 and MET genes is remarkably associated with worse tumor clinicopathologic features and poor prognosis in patients with breast cancer. Further investigations using combination drug regimens targeting PD-L1 and MET are important, particularly in breast tumors expressing high levels of both proteins.

1 month ago

Journal • PD(L)-1 Biomarker • IO biomarker

|

HER-2 (Human epidermal growth factor receptor 2) • PD-L1 (Programmed death ligand 1) • MET (MET proto-oncogene, receptor tyrosine kinase)

|

PD-L1 expression • HER-2 positive • PD-L1 overexpression • MET overexpression • HR negative • MET expression • HER-2 negative + HR negative + PD-L1 expression • HER-2 positive + HR negative • HR negative + HER-2 positive