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DRUG:

GQ1007

i
Other names: GQ1007
Associations
Trials
Company:
BrighGene, GeneQuantum Healthcare
Drug class:
HER2-targeted antibody-drug conjugate, TLR8 agonist, TLR7 agonist
Related drugs:
Associations
Trials
2years
New P1 trial • Combination therapy
|
HER-2 (Human epidermal growth factor receptor 2)
|
HER-2 overexpression • HER-2 mutation • HER-2 underexpression
|
Enweida (envafolimab) • GQ1007
2years
Preclinical Development of CQ1007, HER2 Ab Immune Agonist Conjugate (AIAC) With the Best-in-Class Potential (ADC London 2022)
HER2 is a proven target for breast cancer, gastric cancer and other solid tumours GQ1007 is HER2 AIAC that has been developed using GeneQuantum’s unique iLDC bioconjugation platform, leading excellent druggability and linker stability Review how GQ1007 demonstrates robust in vitro and in vivo anti-tumour activities in multiple preclinical models Evaluate how GQ1007 has the potential to become an important therapeutic option for the HER2+ patients who have progressed on current standard therapies, and a combo opportunity with PD1 therapy
Preclinical
|
HER-2 (Human epidermal growth factor receptor 2)
|
GQ1007
over2years
[VIRTUAL] Preclinical Development of GQ1007, HER2 Ab Immune Agonist Conjugate (AIAC) with the Best-in-class Potential (ADC-USA 2021)
HER2 is a proven target for breast cancer, gastric cancer and other solid tumors GQ1007 is HER2 AIAC that has been developed using GeneQuantum’s unique iLDC bioconjugation platform, leading to excellent druggability and linker stability GQ1007 demonstrates robust in vitro and in vivo anti-tumor activities in multiple preclinical models Discuss GQ1007’s potential to become an important therapeutic option for the HER2+ patients who have progressed on current standard therapies, and a combo opportunity with PD1 therapy Lunch
Preclinical
|
HER-2 (Human epidermal growth factor receptor 2)
|
GQ1007