^
    4d
    Study on the Improvement Effect of Probiotics on Perimenopausal Syndrome in Women with Infertility Induced by Leuprolide (ChiCTR2600117205)
    P=N/A, N=100, Not yet recruiting, Reproductive Hospital Affiliated to Jiangxi University of Traditional Chinese Medicine; Reproductive Hospital Affiliated to Jiangxi University of Trad
    New trial
    |
    leuprolide acetate for depot suspension
    4d
    Comparison of Outcomes Between the GnRH-Agonist Long Protocol and the Intensified Estrogen Protocol for Treating Thin Endometrium in Frozen Embryo Transfer Cycles (ChiCTR2500113652)
    P=N/A, N=282, Not yet recruiting, The First Affiliated Hospital of Wenzhou Medical University; The First Affiliated Hospital of Wenzhou Medical University
    New trial
    4d
    Multidimensional evaluation of different dosage forms of goserelin in the treatment of premenopausal HR+ breast cancer patients based on real-world data (ChiCTR2500112684)
    P=N/A, N=200, Recruiting, First Affiliated Hospital of Zhengzhou University; First Affiliated Hospital of Zhengzhou University
    New trial
    |
    PGR (Progesterone receptor)
    |
    goserelin acetate
    4d
    A randomized crossover trial on the preference of different preparations of goserelin for androgen deprivation therapy (ADT) in patients with prostate cancer (ChiCTR2500111711)
    P=N/A, N=60, Recruiting, The First Affiliated Hospital of Xiamen University; The First Affiliated Hospital of Xiamen University
    New trial
    |
    goserelin acetate
    4d
    A Single-Arm Phase Ⅱ Clinical Study on the Ovarian Protective Effect of Goserelin Microspheres in Adjuvant Chemotherapy for Premenopausal Patients with Early-Stage Breast Cancer (ChiCTR2500112908)
    P2, N=25, Not yet recruiting, China-Japan Union Hospital of Jilin University; China-Japan Union Hospital of Jilin University
    New P2 trial
    |
    goserelin acetate
    4d
    A Phase II, Single-Arm Clinical Study of Goserelin Microspheres for Ovarian Function Preservation During Adjuvant Chemotherapy in Premenopausal Patients with Early Breast Cancer (ChiCTR2500113196)
    P2, N=25, Not yet recruiting, The Third Bethune Hospital of Jilin University; The Third Bethune Hospital of Jilin University
    New P2 trial
    |
    ER (Estrogen receptor)
    |
    ER negative
    |
    goserelin acetate
    4d
    A Randomized, Open-Label, Parallel-Group, Positive-Controlled Phase I Clinical Study Comparing the Pharmacokinetics, Pharmacodynamics, and Safety of Goserelin Acetate Sustained-Release Microspheres for Injection (LY01022) versus Zoladex® 10.8 mg Following Single-Dose Administration in Patients with Prostate Cancer (ChiCTR2500114185)
    P1, N=24, Not yet recruiting, Peking University First Hospital; Peking University First Hospital
    New P1 trial
    6d
    Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics. (PubMed, PLoS One)
    SB may regulate TRP-induced bone metabolism abnormalities in LNCaP cells through the IL-17 signaling pathway as well as five DEPs: p-ERK2, RELA, HSP90B1, GNAI1and GNAI3.
    Journal
    |
    IL17A (Interleukin 17A) • HSP90AB1 (Heat Shock Protein 90 Alpha Family Class B Member 1) • RELA (RELA Proto-Oncogene)
    |
    triptorelin
    7d
    c15-164: AASUR in High Risk Prostate Cancer (clinicaltrials.gov)
    P2, N=64, Completed, Memorial Sloan Kettering Cancer Center | Active, not recruiting --> Completed | Trial completion date: May 2026 --> Jan 2026 | Trial primary completion date: May 2026 --> Jan 2026
    Trial completion • Trial completion date • Trial primary completion date
    |
    abiraterone acetate • apalutamide • leuprolide acetate for depot suspension
    12d
    MESURE: MEdical Versus SUrgical Treatments of Rectal Endometriosis (clinicaltrials.gov)
    P3, N=78, Completed, University Hospital, Rouen | Unknown status --> Completed
    Trial completion
    |
    triptorelin • cyproterone acetate
    27d
    Androgen Receptor Antagonist ARN-509 With or Without Abiraterone Acetate, Gonadotropin-Releasing Hormone Analog, and Prednisone in Treating Patients With High-Risk Prostate Cancer Undergoing Surgery (clinicaltrials.gov)
    P2, N=90, Active, not recruiting, Rutgers, The State University of New Jersey | Trial completion date: Nov 2026 --> Jun 2027 | Trial primary completion date: Nov 2025 --> Jun 2026
    Trial completion date • Trial primary completion date
    |
    abiraterone acetate • prednisone • apalutamide
    28d
    RWE About QOL and Compliance of Patients With OFS in China (clinicaltrials.gov)
    P=N/A, N=562, Completed, Fudan University | Trial completion date: Nov 2024 --> May 2025 | Trial primary completion date: Nov 2024 --> May 2025
    Trial completion date • Trial primary completion date • Real-world evidence • Compliance
    |
    goserelin acetate • leuprolide acetate for depot suspension