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DRUG:

EU204

i
Other names: EBViNT, 4-1BB-based Adoptive T-Cell Therapy, 4-1BB-CTL, EBV-induced Natural T cell, Epstein-Barr virus induced adoptive T-Cell therapy, EU204
Associations
Trials
Company:
Eutilex
Drug class:
CD137 agonist, CD8 T-cell agonist
Related drugs:
Associations
Trials
7ms
Phase 1 trial of 4-1BB-based adoptive T-cell therapy targeting human telomerase reverse transcriptase in patients with advanced refractory solid tumors. (PubMed, Cytotherapy)
The generation of TERTiNTs was feasible and safe and provided an interesting disease control rate in heavily pre-treated cancer patients.
P1 data • Clinical Trial,Phase I • Journal • Metastases
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CD8 (cluster of differentiation 8) • TERT (Telomerase Reverse Transcriptase)
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cyclophosphamide • fludarabine IV • EU204 • EU211