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DRUG:
BDC-2034
i
Other names:
BDC-2034
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News alerts, weekly reports and conference planners
Associations
(1)
News
Trials
Company:
Bolt Biotherap
Drug class:
CEACAM5-targeted antibody-drug conjugate, TLR8 agonist, TLR7 agonist
Related drugs:
‹
SAR408701 (12)
IMMU-130 (2)
EBC-129 (0)
M9140 (0)
imiquimod (4)
SBT6050 (4)
BDC-1001 (2)
SBT6290 (1)
VTX 2337 (1)
BDB018 (0)
CV8102 (0)
EIK1001 (0)
GQ1007 (0)
NKTR-262 (0)
imiquimod intravesical (0)
ZG0895 (0)
STM-416 (0)
TransCon TLR7/8 Agonist (0)
MEDI9197 (0)
AL-034 (0)
APR003 (0)
BNT411 (0)
LHC165 (0)
MBS8 (0)
RG6115 (0)
DSP-0509 (0)
SAR408701 (12)
IMMU-130 (2)
EBC-129 (0)
M9140 (0)
imiquimod (4)
SBT6050 (4)
BDC-1001 (2)
SBT6290 (1)
VTX 2337 (1)
BDB018 (0)
CV8102 (0)
EIK1001 (0)
GQ1007 (0)
NKTR-262 (0)
imiquimod intravesical (0)
ZG0895 (0)
STM-416 (0)
TransCon TLR7/8 Agonist (0)
MEDI9197 (0)
AL-034 (0)
APR003 (0)
BNT411 (0)
LHC165 (0)
MBS8 (0)
RG6115 (0)
DSP-0509 (0)
›
Associations
(1)
News
Trials
Filter by
Latest
over2years
The CEA-targeted ISAC, BDC-2034, shows preclinical efficacy associated with innate immune activation, phagocytosis, and myeloid reprogramming (AACR 2022)
These preclinical findings demonstrate the potential of BDC-2034 to generate anti-tumor activity in CEA-expressing cancers through direct innate immune activation and the induction of adaptive anti-tumor immunity.
over 2 years ago
Preclinical • IO biomarker
|
TNFA (Tumor Necrosis Factor-Alpha) • CEACAM5 (CEA Cell Adhesion Molecule 5) • CXCL10 (Chemokine (C-X-C motif) ligand 10) • CD40 (CD40 Molecule)
|
CEACAM5 expression
|
BDC-2034
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