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    BIOMARKER:

    B2M mutation + MSI-H/dMMR

    i
    Other names: B2M, Beta-2-microglobulin, MSI-H, Microsatellite instability - high, dMMR
    Entrez ID:
    567
    Related biomarkers:
    Expression
    Mutation
    Fusion
    Others
    over1year
    Prevalence and Associations of Beta2-Microglobulin Mutations in MSI-H/dMMR Cancers. (PubMed, Oncologist)
    In conclusion, patients carrying MSI-H/dMMR tumors with B2M mutation showed significantly higher TMB. Prescription of ICIs should be thoroughly evaluated for these patients.
    Journal • Tumor mutational burden • MSi-H Biomarker • IO biomarker
    |
    TMB (Tumor Mutational Burden) • MSI (Microsatellite instability) • B2M (Beta-2-microglobulin)
    |
    TMB-H • MSI-H/dMMR • B2M mutation • B2M mutation + MSI-H/dMMR