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    over1year
    Prevalence and Associations of Beta2-Microglobulin Mutations in MSI-H/dMMR Cancers. (PubMed, Oncologist)
    In conclusion, patients carrying MSI-H/dMMR tumors with B2M mutation showed significantly higher TMB. Prescription of ICIs should be thoroughly evaluated for these patients.
    Journal • Tumor mutational burden • MSi-H Biomarker • IO biomarker
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    TMB (Tumor Mutational Burden) • MSI (Microsatellite instability) • B2M (Beta-2-microglobulin)
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    TMB-H • MSI-H/dMMR • B2M mutation • B2M mutation + MSI-H/dMMR