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DRUG:
ASTX295
i
Other names:
ASTX295, ASTX 295, ASTX-295
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Associations
News
Trials
Company:
Otsuka
Drug class:
MDM2 inhibitor
Related drugs:
‹
KRT-232 (18)
RAIN-32 (13)
RG7388 (10)
APG-115 (9)
CGM097 (4)
ALRN-6924 (3)
HDM201 (3)
MK-8242 (2)
Nutlin-3 (1)
DS-5272 (0)
MI-773 (0)
RG7112 (0)
RG7775 (0)
JNJ-26854165 (0)
KRT-232 (18)
RAIN-32 (13)
RG7388 (10)
APG-115 (9)
CGM097 (4)
ALRN-6924 (3)
HDM201 (3)
MK-8242 (2)
Nutlin-3 (1)
DS-5272 (0)
MI-773 (0)
RG7112 (0)
RG7775 (0)
JNJ-26854165 (0)
›
Associations
News
Trials
Filter by
Latest
4ms
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=106, Active, not recruiting, Taiho Oncology, Inc. | N=250 --> 106
4 months ago
Enrollment change • Metastases
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
TP53 wild-type • MDM2 amplification
|
ASTX295
5ms
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=250, Active, not recruiting, Taiho Oncology, Inc. | Trial primary completion date: Dec 2024 --> May 2024
5 months ago
Trial primary completion date • Metastases
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
ASTX295
1year
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=250, Active, not recruiting, Astex Pharmaceuticals, Inc. | Trial primary completion date: Jun 2025 --> Dec 2024
1 year ago
Trial primary completion date • Metastases
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
TP53 wild-type • MDM2 amplification
|
ASTX295
over1year
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=250, Active, not recruiting, Astex Pharmaceuticals, Inc. | Recruiting --> Active, not recruiting
over 1 year ago
Enrollment closed • Metastases
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
TP53 wild-type • MDM2 amplification
|
ASTX295
over2years
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=250, Recruiting, Astex Pharmaceuticals, Inc. | N=191 --> 250 | Trial completion date: May 2023 --> Aug 2025 | Trial primary completion date: Apr 2023 --> Jun 2025
over 2 years ago
Enrollment change • Trial completion date • Trial primary completion date
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
TP53 wild-type • MDM2 amplification
|
ASTX295
over3years
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=191, Recruiting, Astex Pharmaceuticals, Inc. | Active, not recruiting --> Recruiting
over 3 years ago
Clinical • Enrollment open
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
ASTX295
over3years
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=191, Active, not recruiting, Astex Pharmaceuticals, Inc. | Recruiting --> Active, not recruiting
over 3 years ago
Enrollment closed
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
ASTX295
over3years
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=191, Recruiting, Astex Pharmaceuticals, Inc. | N=135 --> 191
over 3 years ago
Clinical • Enrollment change
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
ASTX295
over4years
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=135, Recruiting, Astex Pharmaceuticals, Inc. | Active, not recruiting --> Recruiting
over 4 years ago
Clinical • Enrollment open
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
ASTX295
almost5years
Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53 (clinicaltrials.gov)
P1/2, N=135, Active, not recruiting, Astex Pharmaceuticals, Inc. | Recruiting --> Active, not recruiting
almost 5 years ago
Clinical • Enrollment closed
|
TP53 (Tumor protein P53) • MDM2 (E3 ubiquitin protein ligase)
|
ASTX295
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