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DRUG:
milademetan (RAIN-32)
i
Other names:
RAIN-32, DS3032b, DS 3032b, DS3032, DS 3032, DS-3032, RAIN 32, RAIN32
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News alerts, weekly reports and conference planners
Associations
(13)
News
Trials
Company:
Daiichi Sankyo, Pathos, Rigel
Drug class:
MDM2 inhibitor
Related drugs:
‹
KRT-232 (18)
RG7388 (10)
APG-115 (9)
CGM097 (4)
ALRN-6924 (3)
HDM201 (3)
MK-8242 (2)
Nutlin-3 (1)
ASTX295 (0)
DS-5272 (0)
MI-773 (0)
RG7112 (0)
RG7775 (0)
JNJ-26854165 (0)
KRT-232 (18)
RG7388 (10)
APG-115 (9)
CGM097 (4)
ALRN-6924 (3)
HDM201 (3)
MK-8242 (2)
Nutlin-3 (1)
ASTX295 (0)
DS-5272 (0)
MI-773 (0)
RG7112 (0)
RG7775 (0)
JNJ-26854165 (0)
›
Associations
(13)
News
Trials
VERI cancer hierarchy
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FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
MDM2 amplification
Solid Tumor
MDM2 amplification
Solid Tumor
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
MDM2 amplification
Liposarcoma
MDM2 amplification
Liposarcoma
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
MDM2 amplification
Sarcoma
MDM2 amplification
Sarcoma
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
GATA3 mutation
Hormone Receptor Positive Breast Cancer
GATA3 mutation
Hormone Receptor Positive Breast Cancer
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
RAIN-32
Sensitive: C2 – Inclusion Criteria
RAIN-32
Sensitive
:
C2
MDM2 amplification + TWIST1 amplification
Sarcoma
MDM2 amplification + TWIST1 amplification
Sarcoma
RAIN-32
Sensitive: C3 – Early Trials
RAIN-32
Sensitive
:
C3
RAIN-32
Sensitive: C3 – Early Trials
RAIN-32
Sensitive
:
C3
MDM2 amplification + TP53 wild-type + TWIST1 amplification
Sarcoma
MDM2 amplification + TP53 wild-type + TWIST1 amplification
Sarcoma
RAIN-32
Sensitive: C3 – Early Trials
RAIN-32
Sensitive
:
C3
RAIN-32
Sensitive: C3 – Early Trials
RAIN-32
Sensitive
:
C3
FLT3-ITD mutation + FLT3 D835Y
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3 D835Y
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive: D – Preclinical
quizartinib + RAIN-32
Sensitive
:
D
quizartinib + RAIN-32
Sensitive: D – Preclinical
quizartinib + RAIN-32
Sensitive
:
D
FLT3-ITD mutation + FLT3 F691L
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3 F691L
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive: D – Preclinical
quizartinib + RAIN-32
Sensitive
:
D
quizartinib + RAIN-32
Sensitive: D – Preclinical
quizartinib + RAIN-32
Sensitive
:
D
TP53 wild-type
Merkel Cell Carcinoma
TP53 wild-type
Merkel Cell Carcinoma
RAIN-32
Sensitive: D – Preclinical
RAIN-32
Sensitive
:
D
RAIN-32
Sensitive: D – Preclinical
RAIN-32
Sensitive
:
D
MDM2 amplification
Hormone Receptor Positive Breast Cancer
MDM2 amplification
Hormone Receptor Positive Breast Cancer
RAIN-32
Sensitive: D – Preclinical
RAIN-32
Sensitive
:
D
RAIN-32
Sensitive: D – Preclinical
RAIN-32
Sensitive
:
D
KRAS G12S
Lung Adenocarcinoma
KRAS G12S
Lung Adenocarcinoma
trametinib + RAIN-32
Sensitive: D – Preclinical
trametinib + RAIN-32
Sensitive
:
D
trametinib + RAIN-32
Sensitive: D – Preclinical
trametinib + RAIN-32
Sensitive
:
D
^
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