Clinical • P2 data • IO biomarker
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BRAF (B-raf proto-oncogene) • TP53 (Tumor protein P53) • BCL2 (B-cell CLL/lymphoma 2) • NOTCH1 (Notch 1) • MYD88 (MYD88 Innate Immune Signal Transduction Adaptor) • SF3B1 (Splicing Factor 3b Subunit 1) • IGH (Immunoglobulin Heavy Locus) • FBXW7 (F-Box And WD Repeat Domain Containing 7) • BIRC3 (Baculoviral IAP repeat containing 3) • POT1 (Protection of telomeres 1) • NFKBIE (NFKB Inhibitor Epsilon)
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TP53 mutation • Chr del(17p) • Chr del(11q) • SF3B1 mutation • IGH mutation • BCL2 mutation
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Venclexta (venetoclax) • Imbruvica (ibrutinib) • Gazyva (obinutuzumab) • Zydelig (idelalisib) • bendamustine • Arzerra (ofatumumab)