^
    over2years
    mTOR pathway gene expression in association with race and clinicopathological characteristics in Black and White breast cancer patients. (PubMed, Discov Oncol)
    Over-expression of RPS6KB2 and EIF4EBP1 and under-expression of TSC1 might be indicators of more aggressive breast cancer phenotypes. Differential expression of AKT1 and RPS6KB2 by race warrants further investigation to elucidate their roles in racial disparities of treatment resistance and outcomes between Black and White women with breast cancer.
    Journal
    |
    AKT1 (V-akt murine thymoma viral oncogene homolog 1) • TSC1 (TSC complex subunit 1) • EIF4EBP1 (Eukaryotic translation initiation factor 4E binding protein 1)
    |
    AKT1 underexpression