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BIOMARKER:

AKT1 mutation + mTOR mutation

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Other names: AKT1, AKT, PKB, PRKBA, RAC, V-akt murine thymoma viral oncogene homolog 1, mTOR, Mechanistic Target Of Rapamycin Kinase, Mammalian Target Of Rapamycin, Rapamycin And FKBP12 Target 1, FK506-Binding Protein 12-Rapamycin Complex-Associated Protein 1, Mechanistic Target Of Rapamycin (Serine/Threonine Kinase), FK506 Binding Protein 12-Rapamycin Associated Protein 2, FKBP12-Rapamycin Complex-Associated Protein 1, Serine/Threonine-Protein Kinase MTOR, Rapamycin Associated Protein FRAP2, FKBP-Rapamycin
Entrez ID:
Related biomarkers:
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Trials
AKT1 mutation + mTOR mutation
Leiomyosarcoma
TAK-228
Sensitive: C3 – Early Trials
AKT1 mutation + mTOR mutation
Endometrial Cancer
TAK-228
Sensitive: C4 – Case Studies
AKT1 mutation + mTOR mutation
Breast Cancer
TAK-228
Sensitive: C4 – Case Studies