^
Contact us  to learn more about
our Premium Content:  News alerts, weekly reports and conference planners
BIOMARKER:

ABCB1 G1236T + ABCB1 G2677T

i
Other names: ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1, ATP-binding cassette, sub-family B (MDR/TAP), member 1
Entrez ID:
Related biomarkers:
over3years
Intracellular vincristine levels in lymphoblasts affect treatment outcome in childhood B-lymphoblastic leukaemia: Ma-Spore ALL 2010 Study. (PubMed, Br J Clin Pharmacol)
We showed that in childhood B-ALL, the intracellular VCR levels in lymphoblasts affected treatment outcomes. The intracellular VCR level was independent of leukaemia subtype but dependent on host ABCB1 G2677T genotype.
Clinical • Journal
|
ABCB1 (ATP Binding Cassette Subfamily B Member 1)
|
ABCB1 G1236T + ABCB1 G2677T • ABCB1 G2677T
|
vincristine
over3years
Association between ABCB1 G2677T/A Polymorphism and Breast Cancer Risk: A Meta-Analysis. (PubMed, Crit Rev Eukaryot Gene Expr)
Similarly, no significant association was observed in the stratification analyses by ethnicity and control source. In conclusion, this meta-analysis suggests that ABCB1 G2677T/A polymorphism is not associated with genetic susceptibility to breast cancer.
Retrospective data • Journal
|
ABCB1 (ATP Binding Cassette Subfamily B Member 1)
|
ABCB1 G1236T + ABCB1 G2677T • ABCB1 G2677T