p53-mutant MB cell line was used to investigate the signaling pathway that regulates proliferation, migration, and drug resistance using inhibitors of HDAC (LBH-589) and PI3K/mTOR [Buparlisib (BKM-120)/rapamycin)]or CUDC-907 (dual inhibitor of HDACs and PI3K/AKT). Results demonstrated that...BKM-120 in combination with mTOR inhibitors suppressed tumor formation...