Associations - Medulloblastoma

CANCER:

Medulloblastoma

Related cancers:

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No biomarker No biomarker	Medulloblastoma Medulloblastoma	carmustine Sensitive: A1 - Approval carmustine Sensitive : A1
No biomarker No biomarker	Medulloblastoma Medulloblastoma	cisplatin + cyclophosphamide oral + vincristine Sensitive: A2 - Guideline cisplatin + cyclophosphamide oral + vincristine Sensitive : A2
No biomarker No biomarker	Medulloblastoma Medulloblastoma	cisplatin + vincristine + lomustine Sensitive: A2 - Guideline cisplatin + vincristine + lomustine Sensitive : A2
PTCH1 mutation PTCH1 mutation	Medulloblastoma Medulloblastoma	vismodegib Sensitive: C3 – Early Trials vismodegib Sensitive : C3
PTCH1 deletion PTCH1 deletion	Medulloblastoma Medulloblastoma	IPI 926 oral Sensitive: D – Preclinical IPI 926 oral Sensitive : D
SUFU deletion SUFU deletion	Medulloblastoma Medulloblastoma	sonidegib Resistant: D – Preclinical sonidegib Resistant : D
MYC expression MYC expression	Medulloblastoma Medulloblastoma	JHU395 Sensitive: D – Preclinical JHU395 Sensitive : D
SMO D477G SMO D477G	Medulloblastoma Medulloblastoma	itraconazole Sensitive: D – Preclinical itraconazole Sensitive : D
MYCN amplification MYCN amplification	Medulloblastoma Medulloblastoma	sonidegib Resistant: D – Preclinical sonidegib Resistant : D
PTCH1 mutation PTCH1 mutation	Medulloblastoma Medulloblastoma	sonidegib Sensitive: D – Preclinical sonidegib Sensitive : D
SUFU mutation SUFU mutation	Medulloblastoma Medulloblastoma	SMO protein inhibitor Resistant: D – Preclinical SMO protein inhibitor Resistant : D
PTCH1 mutation PTCH1 mutation	Medulloblastoma Medulloblastoma	SMO protein inhibitor Sensitive: D – Preclinical SMO protein inhibitor Sensitive : D
SMO D473H SMO D473H	Medulloblastoma Medulloblastoma	vismodegib Resistant: D – Preclinical vismodegib Resistant : D
SMO D473H SMO D473H	Medulloblastoma Medulloblastoma	IPI 926 oral Sensitive: D – Preclinical IPI 926 oral Sensitive : D
TP53 mutation TP53 mutation	Medulloblastoma Medulloblastoma	CUDC-907 Sensitive: D – Preclinical CUDC-907 Sensitive : D
TP53 mutation TP53 mutation	Medulloblastoma Medulloblastoma	BKM120 + panobinostat Sensitive: D – Preclinical BKM120 + panobinostat Sensitive : D
TP53 mutation TP53 mutation	Medulloblastoma Medulloblastoma	panobinostat Sensitive: D – Preclinical panobinostat Sensitive : D
TP53 mutation TP53 mutation	Medulloblastoma Medulloblastoma	BKM120 Resistant: D – Preclinical BKM120 Resistant : D
TP53 mutation TP53 mutation	Medulloblastoma Medulloblastoma	BKM120 + sirolimus Sensitive: D – Preclinical BKM120 + sirolimus Sensitive : D

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