Medulloblastoma

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No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	carmustine Sensitive: A1 - Approval carmustine Sensitive : A1	carmustine Sensitive: A1 - Approval carmustine Sensitive : A1
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cisplatin + cyclophosphamide + vincristine Sensitive: A2 - Guideline cisplatin + cyclophosphamide + vincristine Sensitive : A2	cisplatin + cyclophosphamide + vincristine Sensitive: A2 - Guideline cisplatin + cyclophosphamide + vincristine Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cisplatin + vincristine + lomustine Sensitive: A2 - Guideline cisplatin + vincristine + lomustine Sensitive : A2	cisplatin + vincristine + lomustine Sensitive: A2 - Guideline cisplatin + vincristine + lomustine Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cyclophosphamide Sensitive: A2 - Guideline cyclophosphamide Sensitive : A2	cyclophosphamide Sensitive: A2 - Guideline cyclophosphamide Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	vismodegib Sensitive: A2 - Guideline vismodegib Sensitive : A2	vismodegib Sensitive: A2 - Guideline vismodegib Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cisplatin + cyclophosphamide + etoposide IV Sensitive: A2 - Guideline cisplatin + cyclophosphamide + etoposide IV Sensitive : A2	cisplatin + cyclophosphamide + etoposide IV Sensitive: A2 - Guideline cisplatin + cyclophosphamide + etoposide IV Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	etoposide oral Sensitive: A2 - Guideline etoposide oral Sensitive : A2	etoposide oral Sensitive: A2 - Guideline etoposide oral Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	temozolomide Sensitive: A2 - Guideline temozolomide Sensitive : A2	temozolomide Sensitive: A2 - Guideline temozolomide Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	cyclophosphamide + etoposide oral Sensitive: A2 - Guideline cyclophosphamide + etoposide oral Sensitive : A2	cyclophosphamide + etoposide oral Sensitive: A2 - Guideline cyclophosphamide + etoposide oral Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	carboplatin + cyclophosphamide + etoposide oral Sensitive: A2 - Guideline carboplatin + cyclophosphamide + etoposide oral Sensitive : A2	carboplatin + cyclophosphamide + etoposide oral Sensitive: A2 - Guideline carboplatin + cyclophosphamide + etoposide oral Sensitive : A2
No biomarker	Medulloblastoma	No biomarker	Medulloblastoma	CX-4945 Sensitive: B - Late Trials CX-4945 Sensitive : B	CX-4945 Sensitive: B - Late Trials CX-4945 Sensitive : B
PTCH1 mutation	Medulloblastoma	PTCH1 mutation	Medulloblastoma	vismodegib Sensitive: C3 – Early Trials vismodegib Sensitive : C3	vismodegib Sensitive: C3 – Early Trials vismodegib Sensitive : C3
PTCH1 deletion	Medulloblastoma	PTCH1 deletion	Medulloblastoma	IPI 926 oral Sensitive: D – Preclinical IPI 926 oral Sensitive : D	IPI 926 oral Sensitive: D – Preclinical IPI 926 oral Sensitive : D
SUFU deletion	Medulloblastoma	SUFU deletion	Medulloblastoma	sonidegib Resistant: D – Preclinical sonidegib Resistant : D	sonidegib Resistant: D – Preclinical sonidegib Resistant : D
MYC expression	Medulloblastoma	MYC expression	Medulloblastoma	JHU395 Sensitive: D – Preclinical JHU395 Sensitive : D	JHU395 Sensitive: D – Preclinical JHU395 Sensitive : D
SMO D477G	Medulloblastoma	SMO D477G	Medulloblastoma	itraconazole Sensitive: D – Preclinical itraconazole Sensitive : D	itraconazole Sensitive: D – Preclinical itraconazole Sensitive : D
MYCN amplification	Medulloblastoma	MYCN amplification	Medulloblastoma	sonidegib Resistant: D – Preclinical sonidegib Resistant : D	sonidegib Resistant: D – Preclinical sonidegib Resistant : D
PTCH1 mutation	Medulloblastoma	PTCH1 mutation	Medulloblastoma	sonidegib Sensitive: D – Preclinical sonidegib Sensitive : D	sonidegib Sensitive: D – Preclinical sonidegib Sensitive : D
SUFU mutation	Medulloblastoma	SUFU mutation	Medulloblastoma	SMO protein inhibitor Resistant: D – Preclinical SMO protein inhibitor Resistant : D	SMO protein inhibitor Resistant: D – Preclinical SMO protein inhibitor Resistant : D
PTCH1 mutation	Medulloblastoma	PTCH1 mutation	Medulloblastoma	SMO protein inhibitor Sensitive: D – Preclinical SMO protein inhibitor Sensitive : D	SMO protein inhibitor Sensitive: D – Preclinical SMO protein inhibitor Sensitive : D
SMO D473H	Medulloblastoma	SMO D473H	Medulloblastoma	vismodegib Resistant: D – Preclinical vismodegib Resistant : D	vismodegib Resistant: D – Preclinical vismodegib Resistant : D
SMO D473H	Medulloblastoma	SMO D473H	Medulloblastoma	IPI 926 oral Sensitive: D – Preclinical IPI 926 oral Sensitive : D	IPI 926 oral Sensitive: D – Preclinical IPI 926 oral Sensitive : D
TP53 mutation	Medulloblastoma	TP53 mutation	Medulloblastoma	CUDC-907 Sensitive: D – Preclinical CUDC-907 Sensitive : D	CUDC-907 Sensitive: D – Preclinical CUDC-907 Sensitive : D
TP53 mutation	Medulloblastoma	TP53 mutation	Medulloblastoma	AN2025 + panobinostat Sensitive: D – Preclinical AN2025 + panobinostat Sensitive : D	AN2025 + panobinostat Sensitive: D – Preclinical AN2025 + panobinostat Sensitive : D
TP53 mutation	Medulloblastoma	TP53 mutation	Medulloblastoma	panobinostat Sensitive: D – Preclinical panobinostat Sensitive : D	panobinostat Sensitive: D – Preclinical panobinostat Sensitive : D
TP53 mutation	Medulloblastoma	TP53 mutation	Medulloblastoma	AN2025 Resistant: D – Preclinical AN2025 Resistant : D	AN2025 Resistant: D – Preclinical AN2025 Resistant : D
TP53 mutation	Medulloblastoma	TP53 mutation	Medulloblastoma	AN2025 + sirolimus Sensitive: D – Preclinical AN2025 + sirolimus Sensitive : D	AN2025 + sirolimus Sensitive: D – Preclinical AN2025 + sirolimus Sensitive : D
MYC amplification	Medulloblastoma	MYC amplification	Medulloblastoma	PCM-075 Sensitive: D – Preclinical PCM-075 Sensitive : D	PCM-075 Sensitive: D – Preclinical PCM-075 Sensitive : D
MYCN amplification	Medulloblastoma	MYCN amplification	Medulloblastoma	olaparib + MK-8776 Sensitive: D – Preclinical olaparib + MK-8776 Sensitive : D	olaparib + MK-8776 Sensitive: D – Preclinical olaparib + MK-8776 Sensitive : D

Medulloblastoma

Associations(29)

Associations
(29)