BRCA1 mutation	Ovarian Cancer	BRCA1 mutation	Ovarian Cancer	JPI-547 Sensitive: C2 – Inclusion Criteria JPI-547 Sensitive : C2	JPI-547 Sensitive: C2 – Inclusion Criteria JPI-547 Sensitive : C2
BRCA2 mutation	Non Small Cell Lung Cancer	BRCA2 mutation	Non Small Cell Lung Cancer	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4
ATM mutation	Breast Cancer	ATM mutation	Breast Cancer	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4
BRCA2 mutation	Breast Cancer	BRCA2 mutation	Breast Cancer	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4
BRCA1 mutation	Breast Cancer	BRCA1 mutation	Breast Cancer	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4	JPI-547 Sensitive: C4 – Case Studies JPI-547 Sensitive : C4
APC mutation	Colorectal Cancer	APC mutation	Colorectal Cancer	G007-LK Sensitive: D – Preclinical G007-LK Sensitive : D	G007-LK Sensitive: D – Preclinical G007-LK Sensitive : D
KRAS G12D	Colorectal Cancer	KRAS G12D	Colorectal Cancer	palbociclib + MSC2504877 Resistant: D – Preclinical palbociclib + MSC2504877 Resistant : D	palbociclib + MSC2504877 Resistant: D – Preclinical palbociclib + MSC2504877 Resistant : D
APC mutation	Colorectal Cancer	APC mutation	Colorectal Cancer	STP1002 Sensitive: D – Preclinical STP1002 Sensitive : D	STP1002 Sensitive: D – Preclinical STP1002 Sensitive : D
ARSI overexpression	Squamous Cell Carcinoma of Head and Neck	ARSI overexpression	Squamous Cell Carcinoma of Head and Neck	XAV-939 Sensitive: D – Preclinical XAV-939 Sensitive : D	XAV-939 Sensitive: D – Preclinical XAV-939 Sensitive : D
HRD	Pancreatic Ductal Adenocarcinoma	HRD	Pancreatic Ductal Adenocarcinoma	JPI-547 Sensitive: D – Preclinical JPI-547 Sensitive : D	JPI-547 Sensitive: D – Preclinical JPI-547 Sensitive : D
RNF43 mutation	Pancreatic Ductal Adenocarcinoma	RNF43 mutation	Pancreatic Ductal Adenocarcinoma	JPI-547 Sensitive: D – Preclinical JPI-547 Sensitive : D	JPI-547 Sensitive: D – Preclinical JPI-547 Sensitive : D

TNKS inhibitor

TNKS inhibitor

Associations(11)

Associations
(11)