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BIOMARKER:

TNFRSF8 positive

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Entrez ID:

Related biomarkers:

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RANBP2-ALK rearrangement + TNFRSF8 expression (3)

MYC amplification + BCL2 amplification + TNFRSF8 expression (1)

RANBP2-ALK rearrangement + TNFRSF8 expression (3)

MYC amplification + BCL2 amplification + TNFRSF8 expression (1)

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TNFRSF8 positive	Hodgkin Lymphoma	TNFRSF8 positive	Hodgkin Lymphoma	brentuximab vedotin Sensitive: A1 - Approval brentuximab vedotin Sensitive : A1	brentuximab vedotin Sensitive: A1 - Approval brentuximab vedotin Sensitive : A1
TNFRSF8 positive	Cutaneous T-cell Lymphoma	TNFRSF8 positive	Cutaneous T-cell Lymphoma	brentuximab vedotin Sensitive: A1 - Approval brentuximab vedotin Sensitive : A1	brentuximab vedotin Sensitive: A1 - Approval brentuximab vedotin Sensitive : A1
TNFRSF8 positive	Diffuse Large B Cell Lymphoma	TNFRSF8 positive	Diffuse Large B Cell Lymphoma	brentuximab vedotin Sensitive: A2 - Guideline brentuximab vedotin Sensitive : A2	brentuximab vedotin Sensitive: A2 - Guideline brentuximab vedotin Sensitive : A2
TNFRSF8 positive	Peripheral T-cell Lymphoma	TNFRSF8 positive	Peripheral T-cell Lymphoma	brentuximab vedotin Sensitive: A2 - Guideline brentuximab vedotin Sensitive : A2	brentuximab vedotin Sensitive: A2 - Guideline brentuximab vedotin Sensitive : A2
TNFRSF8 positive	Non-Hodgkin’s Lymphoma	TNFRSF8 positive	Non-Hodgkin’s Lymphoma	TT11 Sensitive: C2 – Inclusion Criteria TT11 Sensitive : C2	TT11 Sensitive: C2 – Inclusion Criteria TT11 Sensitive : C2
TNFRSF8 positive	Lymphoma	TNFRSF8 positive	Lymphoma	AFM13 Sensitive: C2 – Inclusion Criteria AFM13 Sensitive : C2	AFM13 Sensitive: C2 – Inclusion Criteria AFM13 Sensitive : C2
TNFRSF8 positive	Hodgkin Lymphoma	TNFRSF8 positive	Hodgkin Lymphoma	AFM13 Sensitive: C2 – Inclusion Criteria AFM13 Sensitive : C2	AFM13 Sensitive: C2 – Inclusion Criteria AFM13 Sensitive : C2
TNFRSF8 positive	Hodgkin Lymphoma	TNFRSF8 positive	Hodgkin Lymphoma	TT11 Sensitive: C3 – Early Trials TT11 Sensitive : C3	TT11 Sensitive: C3 – Early Trials TT11 Sensitive : C3
TNFRSF8 positive	Peripheral T-cell Lymphoma	TNFRSF8 positive	Peripheral T-cell Lymphoma	Sensitive: C3 – Early Trials Sensitive : C3	Sensitive: C3 – Early Trials Sensitive : C3
TNFRSF8 positive	Hodgkin Lymphoma	TNFRSF8 positive	Hodgkin Lymphoma	CD30-targeted CAR-T immunotherapy Sensitive: C3 – Early Trials CD30-targeted CAR-T immunotherapy Sensitive : C3	CD30-targeted CAR-T immunotherapy Sensitive: C3 – Early Trials CD30-targeted CAR-T immunotherapy Sensitive : C3
TNFRSF8 positive	Non-Hodgkin’s Lymphoma	TNFRSF8 positive	Non-Hodgkin’s Lymphoma	T-lymphocyte cell therapy Sensitive: C3 – Early Trials T-lymphocyte cell therapy Sensitive : C3	T-lymphocyte cell therapy Sensitive: C3 – Early Trials T-lymphocyte cell therapy Sensitive : C3
TNFRSF8 positive	Cutaneous T-cell Lymphoma	TNFRSF8 positive	Cutaneous T-cell Lymphoma	gemcitabine + doxorubicin hydrochloride Sensitive: C3 – Early Trials gemcitabine + doxorubicin hydrochloride Sensitive : C3	gemcitabine + doxorubicin hydrochloride Sensitive: C3 – Early Trials gemcitabine + doxorubicin hydrochloride Sensitive : C3
TNFRSF8 positive	Lymphoma	TNFRSF8 positive	Lymphoma	nivolumab + brentuximab vedotin Sensitive: C3 – Early Trials nivolumab + brentuximab vedotin Sensitive : C3	nivolumab + brentuximab vedotin Sensitive: C3 – Early Trials nivolumab + brentuximab vedotin Sensitive : C3
TNFRSF8 positive	Lymphoma	TNFRSF8 positive	Lymphoma	T-lymphocyte cell therapy Sensitive: D – Preclinical T-lymphocyte cell therapy Sensitive : D	T-lymphocyte cell therapy Sensitive: D – Preclinical T-lymphocyte cell therapy Sensitive : D
TNFRSF8 positive	Non-Hodgkin’s Lymphoma	TNFRSF8 positive	Non-Hodgkin’s Lymphoma	McSAF 02 Sensitive: D – Preclinical McSAF 02 Sensitive : D	McSAF 02 Sensitive: D – Preclinical McSAF 02 Sensitive : D
TNFRSF8 positive	Lymphoma	TNFRSF8 positive	Lymphoma	brentuximab vedotin + SGN-CD30C Sensitive: D – Preclinical brentuximab vedotin + SGN-CD30C Sensitive : D	brentuximab vedotin + SGN-CD30C Sensitive: D – Preclinical brentuximab vedotin + SGN-CD30C Sensitive : D