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BIOMARKER:
TERT mutation
i
Other names:
TERT, Telomerase Reverse Transcriptase, Telomerase-Associated Protein 2, Telomerase Catalytic Subunit, HEST2, EST2, TCS1, TP2, TRT, PFBMFT1, DKCA2, DKCB4, CMM9, HTR
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Entrez ID:
7015
Related biomarkers:
Expression
Mutation
CNA
Others
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Associations
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Trials
VERI cancer hierarchy
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TERT mutation
Solid Tumor
TERT mutation
Solid Tumor
Immunotherapy
Sensitive: C2 – Inclusion Criteria
Immunotherapy
Sensitive
:
C2
Immunotherapy
Sensitive: C2 – Inclusion Criteria
Immunotherapy
Sensitive
:
C2
TERT mutation
Hepatocellular Cancer
TERT mutation
Hepatocellular Cancer
bevacizumab + atezolizumab
Resistant: C3 – Early Trials
bevacizumab + atezolizumab
Resistant
:
C3
bevacizumab + atezolizumab
Resistant: C3 – Early Trials
bevacizumab + atezolizumab
Resistant
:
C3
TERT mutation
Squamous Cell Carcinoma of Head and Neck
TERT mutation
Squamous Cell Carcinoma of Head and Neck
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
TERT mutation
Soft Tissue Sarcoma
TERT mutation
Soft Tissue Sarcoma
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
eribulin mesylate
Sensitive: C3 – Early Trials
eribulin mesylate
Sensitive
:
C3
TERT mutation
Solid Tumor
TERT mutation
Solid Tumor
AST-487
Sensitive: D – Preclinical
AST-487
Sensitive
:
D
AST-487
Sensitive: D – Preclinical
AST-487
Sensitive
:
D
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