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DRUG CLASS:

TEAD1 inhibitor

DRUG CLASS:

TEAD1 inhibitor

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NF2 deletion	Malignant Pleural Mesothelioma	NF2 deletion	Malignant Pleural Mesothelioma	IK-930 Sensitive: B - Late Trials IK-930 Sensitive : B	IK-930 Sensitive: B - Late Trials IK-930 Sensitive : B
KRAS mutation	Mesothelioma	KRAS mutation	Mesothelioma	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D
EGFR mutation	Mesothelioma	EGFR mutation	Mesothelioma	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D
KRAS mutation	Colorectal Cancer	KRAS mutation	Colorectal Cancer	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D
EGFR mutation	Colorectal Cancer	EGFR mutation	Colorectal Cancer	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D
KRAS mutation	Non Small Cell Lung Cancer	KRAS mutation	Non Small Cell Lung Cancer	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D
EGFR mutation	Non Small Cell Lung Cancer	EGFR mutation	Non Small Cell Lung Cancer	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D	IK-930 Sensitive: D – Preclinical IK-930 Sensitive : D