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BIOMARKER:

STRN-ALK rearrangement

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Other names: NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor, STRN, Striatin, Protein Phosphatase 2 Regulatory Subunit B'''Alpha, Striatin Calmodulin Binding Protein, Striatin Calmodulin-Binding Protein, PPP2R6A, SG2NA, STRN1
Entrez ID:
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Trials
STRN-ALK rearrangement
Mesothelioma
crizotinib
Sensitive: C4 – Case Studies
STRN-ALK rearrangement
Mesothelioma
ABT 263
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
cobimetinib
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
ceritinib + PF-05212384
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
X-396
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
trametinib
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
cobimetinib + ceritinib
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
ceritinib
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
brigatinib
Sensitive: D – Preclinical
STRN-ALK rearrangement
Mesothelioma
cisplatin + gemcitabine
Resistant: D – Preclinical