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Association details:
Biomarker:
SRSF2 mutation
Cancer:
Myelodysplastic Syndrome
Drug:
Jakafi (ruxolitinib)
(
JAK2 inhibitor
,
JAK1 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Myelodysplastic…Subtype...CMML-2…Frequent mutations...TET2, SRSF2, ASXl1, RUNX1, NRAS, CBL…HMA ± ruxolitinib…
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