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BIOMARKER:

SRSF2 mutation

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Entrez ID:

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SRSF2 mutation	Myelodysplastic Syndrome	SRSF2 mutation	Myelodysplastic Syndrome	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2	ruxolitinib Sensitive: A2 - Guideline ruxolitinib Sensitive : A2
SRSF2 mutation	Acute Myelogenous Leukemia	SRSF2 mutation	Acute Myelogenous Leukemia	lenalidomide Sensitive: B - Late Trials lenalidomide Sensitive : B	lenalidomide Sensitive: B - Late Trials lenalidomide Sensitive : B
SRSF2 mutation	Acute Myelogenous Leukemia	SRSF2 mutation	Acute Myelogenous Leukemia	LY3009120 Resistant: C3 – Early Trials LY3009120 Resistant : C3	LY3009120 Resistant: C3 – Early Trials LY3009120 Resistant : C3
SRSF2 mutation	Acute Myelogenous Leukemia	SRSF2 mutation	Acute Myelogenous Leukemia	AZD1775 Sensitive: C3 – Early Trials AZD1775 Sensitive : C3	AZD1775 Sensitive: C3 – Early Trials AZD1775 Sensitive : C3
SRSF2 mutation	Acute Myelogenous Leukemia	SRSF2 mutation	Acute Myelogenous Leukemia	ACR-368 Sensitive: C3 – Early Trials ACR-368 Sensitive : C3	ACR-368 Sensitive: C3 – Early Trials ACR-368 Sensitive : C3
SRSF2 mutation	Acute Myelogenous Leukemia	SRSF2 mutation	Acute Myelogenous Leukemia	venetoclax Sensitive: C3 – Early Trials venetoclax Sensitive : C3	venetoclax Sensitive: C3 – Early Trials venetoclax Sensitive : C3
SRSF2 mutation	Myelodysplastic Syndrome	SRSF2 mutation	Myelodysplastic Syndrome	venetoclax Sensitive: C3 – Early Trials venetoclax Sensitive : C3	venetoclax Sensitive: C3 – Early Trials venetoclax Sensitive : C3
SRSF2 mutation	Acute Myelogenous Leukemia	SRSF2 mutation	Acute Myelogenous Leukemia	TP-0903 Resistant: D – Preclinical TP-0903 Resistant : D	TP-0903 Resistant: D – Preclinical TP-0903 Resistant : D