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    BIOMARKER:

    SMAD4 deletion

    i
    Other names: HSMAD4, Mothers Against DPP Homolog 4, SMAD, Mothers Against DPP Homolog 4, Deleted In Pancreatic Carcinoma Locus 4, SMAD, Mothers Against DPP Homolog 4, Mothers Against Decapentaplegic, Drosophila, Homolog Of, 4, MADH4, MAD, Mothers Against Decapentaplegic Homolog 4, Mothers Against Decapentaplegic Homolog 4, MAD Homolog 4, SMAD4, SMAD Family Member 4, Deletion Target In Pancreatic Carcinoma 4
    Entrez ID:
    4089
    Related biomarkers:
    Expression
    Mutation
    SMAD4 deletion
    Pancreatic Adenocarcinoma
    gemcitabine + albumin-bound paclitaxel + hydroxychloroquine
    Sensitive: C3 – Early Trials
    SMAD4 deletion
    SCCHN
    cetuximab
    Resistant: D – Preclinical