ER negative	Breast Cancer	ER negative	Breast Cancer	toremifene Resistant: A1 - Approval toremifene Resistant : A1	toremifene Resistant: A1 - Approval toremifene Resistant : A1
No biomarker	Breast Cancer	No biomarker	Breast Cancer	toremifene Sensitive: A1 - Approval toremifene Sensitive : A1	toremifene Sensitive: A1 - Approval toremifene Sensitive : A1
ER positive	Estrogen Receptor Positive Breast Cancer	ER positive	Estrogen Receptor Positive Breast Cancer	toremifene Sensitive: A1 - Approval toremifene Sensitive : A1	toremifene Sensitive: A1 - Approval toremifene Sensitive : A1
HR positive	HER2 Negative Breast Cancer	HR positive	HER2 Negative Breast Cancer	toremifene Sensitive: A2 - Guideline toremifene Sensitive : A2	toremifene Sensitive: A2 - Guideline toremifene Sensitive : A2
ER positive	Estrogen Receptor Positive Breast Cancer	ER positive	Estrogen Receptor Positive Breast Cancer	Z-endoxifen hydrochloride Sensitive: C2 – Inclusion Criteria Z-endoxifen hydrochloride Sensitive : C2	Z-endoxifen hydrochloride Sensitive: C2 – Inclusion Criteria Z-endoxifen hydrochloride Sensitive : C2
ESR1 mutation	HER2 Negative Breast Cancer	ESR1 mutation	HER2 Negative Breast Cancer	lasofoxifene Sensitive: C2 – Inclusion Criteria lasofoxifene Sensitive : C2	lasofoxifene Sensitive: C2 – Inclusion Criteria lasofoxifene Sensitive : C2
HR positive	Hormone Receptor Positive Breast Cancer	HR positive	Hormone Receptor Positive Breast Cancer	Z-endoxifen hydrochloride Sensitive: C3 – Early Trials Z-endoxifen hydrochloride Sensitive : C3	Z-endoxifen hydrochloride Sensitive: C3 – Early Trials Z-endoxifen hydrochloride Sensitive : C3
FGFR1 amplification	Breast Cancer	FGFR1 amplification	Breast Cancer	afimoxifene Resistant: D – Preclinical afimoxifene Resistant : D	afimoxifene Resistant: D – Preclinical afimoxifene Resistant : D
ER Y537S	Estrogen Receptor Positive Breast Cancer	ER Y537S	Estrogen Receptor Positive Breast Cancer	lasofoxifene Sensitive: D – Preclinical lasofoxifene Sensitive : D	lasofoxifene Sensitive: D – Preclinical lasofoxifene Sensitive : D
ER D538G	Estrogen Receptor Positive Breast Cancer	ER D538G	Estrogen Receptor Positive Breast Cancer	lasofoxifene Sensitive: D – Preclinical lasofoxifene Sensitive : D	lasofoxifene Sensitive: D – Preclinical lasofoxifene Sensitive : D
ER positive	Estrogen Receptor Positive Breast Cancer	ER positive	Estrogen Receptor Positive Breast Cancer	doxorubicin hydrochloride + Z-endoxifen Sensitive: D – Preclinical doxorubicin hydrochloride + Z-endoxifen Sensitive : D	doxorubicin hydrochloride + Z-endoxifen Sensitive: D – Preclinical doxorubicin hydrochloride + Z-endoxifen Sensitive : D

Selective estrogen receptor modulator

Selective estrogen receptor modulator

Associations(11)

Associations
(11)