Rubraca (rucaparib)

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Company:

Clovis, Pharma& Schweiz

Drug class:

PARP inhibitor

Related drugs:

No biomarker	Peritoneal Cancer	No biomarker	Peritoneal Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA1 mutation	Peritoneal Cancer	BRCA1 mutation	Peritoneal Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA2 mutation	Peritoneal Cancer	BRCA2 mutation	Peritoneal Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA1 mutation	Fallopian Tube Cancer	BRCA1 mutation	Fallopian Tube Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA2 mutation	Fallopian Tube Cancer	BRCA2 mutation	Fallopian Tube Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
No biomarker	Fallopian Tube Cancer	No biomarker	Fallopian Tube Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA1 mutation	Ovarian Cancer	BRCA1 mutation	Ovarian Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA2 mutation	Ovarian Cancer	BRCA2 mutation	Ovarian Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
No biomarker	Ovarian Cancer	No biomarker	Ovarian Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA1 mutation	Prostate Cancer	BRCA1 mutation	Prostate Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
BRCA2 mutation	Prostate Cancer	BRCA2 mutation	Prostate Cancer	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1	rucaparib Sensitive: A1 - Approval rucaparib Sensitive : A1
HRD	Ovarian Cancer	HRD	Ovarian Cancer	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2
PALB2 mutation	Pancreatic Adenocarcinoma	PALB2 mutation	Pancreatic Adenocarcinoma	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2
BRCA2 mutation	Pancreatic Adenocarcinoma	BRCA2 mutation	Pancreatic Adenocarcinoma	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2
BRCA1 mutation	Pancreatic Adenocarcinoma	BRCA1 mutation	Pancreatic Adenocarcinoma	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2
BRCA wild-type	Ovarian Cancer	BRCA wild-type	Ovarian Cancer	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2	rucaparib Sensitive: A2 - Guideline rucaparib Sensitive : A2
RAD51D mutation	Ovarian Cancer	RAD51D mutation	Ovarian Cancer	rucaparib Sensitive: B - Late Trials rucaparib Sensitive : B	rucaparib Sensitive: B - Late Trials rucaparib Sensitive : B
RAD51C mutation	Ovarian Cancer	RAD51C mutation	Ovarian Cancer	rucaparib Sensitive: B - Late Trials rucaparib Sensitive : B	rucaparib Sensitive: B - Late Trials rucaparib Sensitive : B
ATM mutation	Prostate Cancer	ATM mutation	Prostate Cancer	rucaparib Sensitive: B - Late Trials rucaparib Sensitive : B	rucaparib Sensitive: B - Late Trials rucaparib Sensitive : B
BRCA2 mutation	Non Small Cell Lung Cancer	BRCA2 mutation	Non Small Cell Lung Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA1 mutation	Non Small Cell Lung Cancer	BRCA1 mutation	Non Small Cell Lung Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA2 mutation	Pancreatic Cancer	BRCA2 mutation	Pancreatic Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA1 mutation	Pancreatic Cancer	BRCA1 mutation	Pancreatic Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA1 mutation	Mesothelioma	BRCA1 mutation	Mesothelioma	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA1 mutation	Triple Negative Breast Cancer	BRCA1 mutation	Triple Negative Breast Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA2 mutation	Gastrointestinal Cancer	BRCA2 mutation	Gastrointestinal Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA1 mutation	Gastrointestinal Cancer	BRCA1 mutation	Gastrointestinal Cancer	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1	rucaparib Sensitive: C1 - Off-label rucaparib Sensitive : C1
BRCA2 mutation	Triple Negative Breast Cancer	BRCA2 mutation	Triple Negative Breast Cancer	rucaparib Resistant: C1 - Off-label rucaparib Resistant : C1	rucaparib Resistant: C1 - Off-label rucaparib Resistant : C1
ATM mutation	Solid Tumor	ATM mutation	Solid Tumor	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2
FANCA mutation	Prostate Cancer	FANCA mutation	Prostate Cancer	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2
BRIP1 mutation	Prostate Cancer	BRIP1 mutation	Prostate Cancer	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2
PALB2 mutation	Pancreatic Cancer	PALB2 mutation	Pancreatic Cancer	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2	rucaparib Sensitive: C2 – Inclusion Criteria rucaparib Sensitive : C2

Rubraca (rucaparib)

Associations
(71)

Associations
(71)

Rubraca (rucaparib)

Associations(71)

Associations(71)

Associations
(71)

Associations
(71)