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DRUG:

Partruvix (pamiparib)

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News alerts, weekly reports and conference planners

Company:

BeiGene, EMD Serono

Drug class:

PARP inhibitor

Related drugs:

BRCA1 mutation	Fallopian Tube Cancer	BRCA1 mutation	Fallopian Tube Cancer	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1
BRCA2 mutation	Ovarian Cancer	BRCA2 mutation	Ovarian Cancer	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1
BRCA1 mutation	Ovarian Cancer	BRCA1 mutation	Ovarian Cancer	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1
BRCA2 mutation	Peritoneal Cancer	BRCA2 mutation	Peritoneal Cancer	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1
BRCA1 mutation	Peritoneal Cancer	BRCA1 mutation	Peritoneal Cancer	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1
BRCA2 mutation	Fallopian Tube Cancer	BRCA2 mutation	Fallopian Tube Cancer	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1	pamiparib Sensitive: A1 - Approval pamiparib Sensitive : A1
BRCA2 mutation	Triple Negative Breast Cancer	BRCA2 mutation	Triple Negative Breast Cancer	pamiparib Sensitive: C1 - Off-label pamiparib Sensitive : C1	pamiparib Sensitive: C1 - Off-label pamiparib Sensitive : C1
BRCA1 mutation	Triple Negative Breast Cancer	BRCA1 mutation	Triple Negative Breast Cancer	pamiparib Sensitive: C1 - Off-label pamiparib Sensitive : C1	pamiparib Sensitive: C1 - Off-label pamiparib Sensitive : C1
BRCA1 mutation	Triple Negative Breast Cancer	BRCA1 mutation	Triple Negative Breast Cancer	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2
IDH2 mutation	Glioma	IDH2 mutation	Glioma	pamiparib Sensitive: C2 – Inclusion Criteria pamiparib Sensitive : C2	pamiparib Sensitive: C2 – Inclusion Criteria pamiparib Sensitive : C2
HRD	Ovarian Cancer	HRD	Ovarian Cancer	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2
BRCA2 mutation	Ovarian Cancer	BRCA2 mutation	Ovarian Cancer	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2
BRCA1 mutation	Ovarian Cancer	BRCA1 mutation	Ovarian Cancer	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2
BRCA2 mutation	Triple Negative Breast Cancer	BRCA2 mutation	Triple Negative Breast Cancer	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2	tislelizumab-jsgr + pamiparib Sensitive: C2 – Inclusion Criteria tislelizumab-jsgr + pamiparib Sensitive : C2
BRCA2 mutation + HR positive	HER2 Negative Breast Cancer	BRCA2 mutation + HR positive	HER2 Negative Breast Cancer	pamiparib Sensitive: C3 – Early Trials pamiparib Sensitive : C3	pamiparib Sensitive: C3 – Early Trials pamiparib Sensitive : C3
BRCA1 mutation + HR positive	HER2 Negative Breast Cancer	BRCA1 mutation + HR positive	HER2 Negative Breast Cancer	pamiparib Sensitive: C3 – Early Trials pamiparib Sensitive : C3	pamiparib Sensitive: C3 – Early Trials pamiparib Sensitive : C3
RAD50 I371Ffs*8	Ovarian Cancer	RAD50 I371Ffs*8	Ovarian Cancer	bevacizumab + pamiparib Sensitive: C4 – Case Studies bevacizumab + pamiparib Sensitive : C4	bevacizumab + pamiparib Sensitive: C4 – Case Studies bevacizumab + pamiparib Sensitive : C4
IDH1 mutation	Glioma	IDH1 mutation	Glioma	pamiparib Sensitive: D – Preclinical pamiparib Sensitive : D	pamiparib Sensitive: D – Preclinical pamiparib Sensitive : D