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BIOMARKER:

RRM2 overexpression

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Other names: RRM2, Ribonucleotide Reductase Regulatory Subunit M2, Ribonucleoside-Diphosphate Reductase Subunit M2, Ribonucleotide Reductase M2 Polypeptide, Ribonucleotide Reductase Small Subunit, Ribonucleotide Reductase Small Chain, RR2, Chromosome 2 Open Reading Frame 48, Uncharacterized Protein C2orf48, FLJ25102, C2orf48, RR2M, R2
Entrez ID:
RRM2 overexpression
HER2 Positive Breast Cancer
ado-trastuzumab emtansine
Sensitive: C3 – Early Trials
Cancer - 2 weeks
RRM2 overexpression
HCC
ARQ 197
Sensitive: D – Preclinical