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BIOMARKER:

ROS1 mutation

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Other names: ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, V-Ros Avian UR2 Sarcoma Virus Oncogene Homolog 1, C-Ros Oncogene 1 Receptor Tyrosine Kinase, Proto-Oncogene Tyrosine-Protein Kinase ROS, Proto-Oncogene C-Ros-1, MCF3, ROS, V-Ros UR2 Sarcoma Virus Oncogene Homolog 1 (Avian), ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, Transmembrane Tyrosine-Specific Protein Kinase, Receptor Tyrosine Kinase C-Ros Oncogene 1, C-Ros Receptor Tyrosine Kinase, Proto-oncogene C-Ros, C-Ros-1
Entrez ID:
ROS1 mutation
NSCLC
VEGFR-2 inhibitor
Sensitive: C3 – Early Trials
ROS1 mutation
NSCLC
entrectinib
Resistant: C3 – Early Trials
ROS1 mutation
Solid Tumor
Immunotherapy
Sensitive: C3 – Early Trials
ROS1 mutation
NSCLC
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
ROS1 mutation
NSCLC
TPX-0005
Sensitive: D – Preclinical