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BIOMARKER:
ROS1 mutation
i
Other names:
ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, V-Ros Avian UR2 Sarcoma Virus Oncogene Homolog 1, C-Ros Oncogene 1 Receptor Tyrosine Kinase, Proto-Oncogene Tyrosine-Protein Kinase ROS, Proto-Oncogene C-Ros-1, MCF3, ROS, V-Ros UR2 Sarcoma Virus Oncogene Homolog 1 (Avian), ROS Proto-Oncogene 1 Receptor Tyrosine Kinase, Transmembrane Tyrosine-Specific Protein Kinase, Receptor Tyrosine Kinase C-Ros Oncogene 1, C-Ros Receptor Tyrosine Kinase, Proto-oncogene C-Ros, C-Ros-1
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Entrez ID:
6098
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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Trials
VERI cancer hierarchy
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ROS1 mutation
Non Small Cell Lung Cancer
ROS1 mutation
Non Small Cell Lung Cancer
VEGFR-2 inhibitor
Sensitive: C3 – Early Trials
VEGFR-2 inhibitor
Sensitive
:
C3
VEGFR-2 inhibitor
Sensitive: C3 – Early Trials
VEGFR-2 inhibitor
Sensitive
:
C3
ROS1 mutation
Non Small Cell Lung Cancer
ROS1 mutation
Non Small Cell Lung Cancer
entrectinib
Resistant: C3 – Early Trials
entrectinib
Resistant
:
C3
entrectinib
Resistant: C3 – Early Trials
entrectinib
Resistant
:
C3
ROS1 mutation
Solid Tumor
ROS1 mutation
Solid Tumor
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
ROS1 mutation
Non Small Cell Lung Cancer
ROS1 mutation
Non Small Cell Lung Cancer
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
Tyrosine kinase inhibitor
Sensitive
:
C3
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
Tyrosine kinase inhibitor
Sensitive
:
C3
ROS1 mutation
Head and Neck Cancer
ROS1 mutation
Head and Neck Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
ROS1 mutation
Non Small Cell Lung Cancer
ROS1 mutation
Non Small Cell Lung Cancer
crizotinib
Sensitive: C4 – Case Studies
crizotinib
Sensitive
:
C4
crizotinib
Sensitive: C4 – Case Studies
crizotinib
Sensitive
:
C4
ROS1 mutation
Non Small Cell Lung Cancer
ROS1 mutation
Non Small Cell Lung Cancer
repotrectinib
Sensitive: D – Preclinical
repotrectinib
Sensitive
:
D
repotrectinib
Sensitive: D – Preclinical
repotrectinib
Sensitive
:
D
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