No biomarker	Small Cell Lung Cancer	No biomarker	Small Cell Lung Cancer	lurbinectedin Sensitive: A1 - Approval lurbinectedin Sensitive : A1	lurbinectedin Sensitive: A1 - Approval lurbinectedin Sensitive : A1
No biomarker	Ewing Sarcoma	No biomarker	Ewing Sarcoma	lurbinectedin Sensitive: A2 - Guideline lurbinectedin Sensitive : A2	lurbinectedin Sensitive: A2 - Guideline lurbinectedin Sensitive : A2
BRCA2 mutation	Breast Cancer	BRCA2 mutation	Breast Cancer	lurbinectedin Sensitive: C2 – Inclusion Criteria lurbinectedin Sensitive : C2	lurbinectedin Sensitive: C2 – Inclusion Criteria lurbinectedin Sensitive : C2
BRCA1 mutation	Breast Cancer	BRCA1 mutation	Breast Cancer	lurbinectedin Sensitive: C2 – Inclusion Criteria lurbinectedin Sensitive : C2	lurbinectedin Sensitive: C2 – Inclusion Criteria lurbinectedin Sensitive : C2
SLFN11 overexpression	Small Cell Lung Cancer	SLFN11 overexpression	Small Cell Lung Cancer	lurbinectedin Sensitive: D – Preclinical lurbinectedin Sensitive : D	lurbinectedin Sensitive: D – Preclinical lurbinectedin Sensitive : D
SLFN11 underexpression	Small Cell Lung Cancer	SLFN11 underexpression	Small Cell Lung Cancer	M6620 + lurbinectedin Sensitive: D – Preclinical M6620 + lurbinectedin Sensitive : D	M6620 + lurbinectedin Sensitive: D – Preclinical M6620 + lurbinectedin Sensitive : D
SLFN11 underexpression	Small Cell Lung Cancer	SLFN11 underexpression	Small Cell Lung Cancer	AZD6738 + lurbinectedin Sensitive: D – Preclinical AZD6738 + lurbinectedin Sensitive : D	AZD6738 + lurbinectedin Sensitive: D – Preclinical AZD6738 + lurbinectedin Sensitive : D
POU2F3 overexpression	Small Cell Lung Cancer	POU2F3 overexpression	Small Cell Lung Cancer	lurbinectedin Sensitive: D – Preclinical lurbinectedin Sensitive : D	lurbinectedin Sensitive: D – Preclinical lurbinectedin Sensitive : D
ERCC5 overexpression	Small Cell Lung Cancer	ERCC5 overexpression	Small Cell Lung Cancer	M6620 + lurbinectedin Sensitive: D – Preclinical M6620 + lurbinectedin Sensitive : D	M6620 + lurbinectedin Sensitive: D – Preclinical M6620 + lurbinectedin Sensitive : D
SLFN11 overexpression	Small Cell Lung Cancer	SLFN11 overexpression	Small Cell Lung Cancer	M6620 + lurbinectedin Sensitive: D – Preclinical M6620 + lurbinectedin Sensitive : D	M6620 + lurbinectedin Sensitive: D – Preclinical M6620 + lurbinectedin Sensitive : D
EGFR mutation	Lung Adenocarcinoma	EGFR mutation	Lung Adenocarcinoma	lurbinectedin Sensitive: D – Preclinical lurbinectedin Sensitive : D	lurbinectedin Sensitive: D – Preclinical lurbinectedin Sensitive : D

RNA polymerase inhibitor

RNA polymerase inhibitor

Associations(11)

Associations
(11)