^
BIOMARKER:

PTPN11 mutation

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Other names: PTPN11, Protein Tyrosine Phosphatase Non-Receptor Type 11, Tyrosine-Protein Phosphatase Non-Receptor Type 11, Protein-Tyrosine Phosphatase 1D, Protein-Tyrosine Phosphatase 2C, SH-PTP2, SH-PTP3, PTP-1D, PTP2C, Protein Tyrosine Phosphatase Non-Receptor Type 11, Noonan Syndrome 1, METCDS, PTP-2C, SHPTP2, BPTP3, SHP-2, JMML, SHP2, Shp2, CFC, NS1
Entrez ID:
Related biomarkers:
PTPN11 mutation
AML
gilteritinib
Resistant: B - Late Trials
PTPN11 mutation
AML
LY3009120
Sensitive: C3 – Early Trials
PTPN11 mutation
AML
venetoclax
Resistant: C3 – Early Trials
PTPN11 mutation
AML
cytarabine + daunorubicin + mitoxantrone
Sensitive: C3 – Early Trials
PTPN11 mutation
AML
ivosidenib
Resistant: C3 – Early Trials
PTPN11 mutation
AML
venetoclax + ABBV 075
Sensitive: C3 – Early Trials
PTPN11 mutation
AML
dasatinib
Sensitive: D – Preclinical