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Association details:
| Biomarker: | PTEN mutation |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | bicalutamide (Androgen receptor inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Association of PTEN Status with Response to Salvage Radiation Therapy with or without Anti-Androgen Therapy: A Study of RTOG 96-01
Published date:
03/02/2020
Excerpt:
...we performed PTEN immunohistochemistry on primary prostate cancer (PCa) from 146 patients treated with RT/AAT vs. 160 patients treated with RT alone....anti-androgen therapy (AAT) with bicalutamide at the time of radiation therapy (RT)...PTEN loss was non-significantly associated with MFS (HR=1.20; 95% CI: 0.72-1.98).
Trial ID:
