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BIOMARKER:

PPP2R2A mutation

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Other names: Protein Phosphatase 2 Regulatory Subunit B Alpha, Serine/Threonine-Protein Phosphatase 2A 55 KDa Regulatory, Subunit B Alpha Isoform, PP2A Subunit B Isoform Alpha, Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit B (PR 52), Alpha Isoform, PP2A Subunit B Isoform PR55-Alpha, PP2A Subunit B Isoform B55-Alpha, PP2A Subunit B Isoform R2-Alpha, PR55alpha, B55ALPHA, PR52A, PR55A
Entrez ID:
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Trials
PPP2R2A mutation
Prostate Cancer
olaparib
Resistant: A2 - Guideline
PPP2R2A mutation
Ovarian Cancer
olaparib
Sensitive: B - Late Trials
PPP2R2A mutation
HER2 Negative Breast Cancer
durvalumab
Sensitive: C2 – Inclusion Criteria