^
Association details:
Biomarker:PPP2R2A mutation
Cancer:Prostate Cancer
Drug:Lynparza (olaparib) (PARP inhibitor)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: A2 - Guideline
Source:
Published date:
05/21/2020
Excerpt:
...Patients with PPP2RA mutations in the profound trial experienced an unfavorable risk benefit profile. Therefore olaparib is not recommended in patients with PPP2RA mutations.