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DRUG CLASS:
Apoptosis stimulant
DRUG CLASS:
Apoptosis stimulant
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News alerts, weekly reports and conference planners
Related drugs:
‹
lurbinectedin (11)
arsenic trioxide (6)
STA-4783 (5)
pelareorep (4)
omacetaxine mepesuccinate (4)
GZ17-6.02 (3)
quaratusugene ozeplasmid (3)
BAL101553 (3)
teserpaturev (1)
IT-141 (1)
Alpha1H (1)
NEO100 (1)
ABI-1968 topical cream (0)
APTO-253 (0)
BP-C1 (0)
BXQ-350 (0)
CM-728 (0)
IL-17E (0)
autologous γδ T lymphocytes (0)
KLTi (0)
MT-3724 (0)
84AA-API 14AA (0)
PVT-1 (0)
SVV-001 (0)
alpha-tocopheroloxyacetic acid (0)
darinaparsin (0)
AFP-464 (0)
elemene injection (0)
BAY1862864 (0)
BS-HH-002.SA (0)
PT-112 (0)
K-333 (0)
piceatannol (0)
AP1903 (0)
PRX302 (0)
lurbinectedin (11)
arsenic trioxide (6)
STA-4783 (5)
pelareorep (4)
omacetaxine mepesuccinate (4)
GZ17-6.02 (3)
quaratusugene ozeplasmid (3)
BAL101553 (3)
teserpaturev (1)
IT-141 (1)
Alpha1H (1)
NEO100 (1)
ABI-1968 topical cream (0)
APTO-253 (0)
BP-C1 (0)
BXQ-350 (0)
CM-728 (0)
IL-17E (0)
autologous γδ T lymphocytes (0)
KLTi (0)
MT-3724 (0)
84AA-API 14AA (0)
PVT-1 (0)
SVV-001 (0)
alpha-tocopheroloxyacetic acid (0)
darinaparsin (0)
AFP-464 (0)
elemene injection (0)
BAY1862864 (0)
BS-HH-002.SA (0)
PT-112 (0)
K-333 (0)
piceatannol (0)
AP1903 (0)
PRX302 (0)
›
Associations
(43)
News
Trials
VERI cancer hierarchy
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No biomarker
Chronic Myeloid Leukemia
No biomarker
Chronic Myeloid Leukemia
omacetaxine mepesuccinate
Sensitive: A1 - Approval
omacetaxine mepesuccinate
Sensitive
:
A1
omacetaxine mepesuccinate
Sensitive: A1 - Approval
omacetaxine mepesuccinate
Sensitive
:
A1
No biomarker
Small Cell Lung Cancer
No biomarker
Small Cell Lung Cancer
lurbinectedin
Sensitive: A1 - Approval
lurbinectedin
Sensitive
:
A1
lurbinectedin
Sensitive: A1 - Approval
lurbinectedin
Sensitive
:
A1
Chr t(15;17)
Acute Promyelocytic Leukemia
Chr t(15;17)
Acute Promyelocytic Leukemia
arsenic trioxide
Sensitive: A1 - Approval
arsenic trioxide
Sensitive
:
A1
arsenic trioxide
Sensitive: A1 - Approval
arsenic trioxide
Sensitive
:
A1
PML-RARA fusion
Acute Promyelocytic Leukemia
PML-RARA fusion
Acute Promyelocytic Leukemia
arsenic trioxide
Sensitive: A1 - Approval
arsenic trioxide
Sensitive
:
A1
arsenic trioxide
Sensitive: A1 - Approval
arsenic trioxide
Sensitive
:
A1
No biomarker
Glioma
No biomarker
Glioma
teserpaturev
Sensitive: A1 - Approval
teserpaturev
Sensitive
:
A1
teserpaturev
Sensitive: A1 - Approval
teserpaturev
Sensitive
:
A1
No biomarker
Ewing Sarcoma
No biomarker
Ewing Sarcoma
lurbinectedin
Sensitive: A2 - Guideline
lurbinectedin
Sensitive
:
A2
lurbinectedin
Sensitive: A2 - Guideline
lurbinectedin
Sensitive
:
A2
No biomarker
Non Small Cell Lung Cancer
No biomarker
Non Small Cell Lung Cancer
pembrolizumab + quaratusugene ozeplasmid
Sensitive: B - Late Trials
pembrolizumab + quaratusugene ozeplasmid
Sensitive
:
B
pembrolizumab + quaratusugene ozeplasmid
Sensitive: B - Late Trials
pembrolizumab + quaratusugene ozeplasmid
Sensitive
:
B
No biomarker
Pancreatic Ductal Adenocarcinoma
No biomarker
Pancreatic Ductal Adenocarcinoma
atezolizumab + pelareorep
Sensitive: B - Late Trials
atezolizumab + pelareorep
Sensitive
:
B
atezolizumab + pelareorep
Sensitive: B - Late Trials
atezolizumab + pelareorep
Sensitive
:
B
No biomarker
Small Cell Lung Cancer
No biomarker
Small Cell Lung Cancer
atezolizumab + quaratusugene ozeplasmid
Sensitive: B - Late Trials
atezolizumab + quaratusugene ozeplasmid
Sensitive
:
B
atezolizumab + quaratusugene ozeplasmid
Sensitive: B - Late Trials
atezolizumab + quaratusugene ozeplasmid
Sensitive
:
B
No biomarker
Bladder Cancer
No biomarker
Bladder Cancer
Alpha1H
Sensitive: B - Late Trials
Alpha1H
Sensitive
:
B
Alpha1H
Sensitive: B - Late Trials
Alpha1H
Sensitive
:
B
IDH1 mutation
Glioblastoma
IDH1 mutation
Glioblastoma
NEO100
Sensitive: C2 – Inclusion Criteria
NEO100
Sensitive
:
C2
NEO100
Sensitive: C2 – Inclusion Criteria
NEO100
Sensitive
:
C2
BRCA2 mutation
Breast Cancer
BRCA2 mutation
Breast Cancer
lurbinectedin
Sensitive: C2 – Inclusion Criteria
lurbinectedin
Sensitive
:
C2
lurbinectedin
Sensitive: C2 – Inclusion Criteria
lurbinectedin
Sensitive
:
C2
BRCA1 mutation
Breast Cancer
BRCA1 mutation
Breast Cancer
lurbinectedin
Sensitive: C2 – Inclusion Criteria
lurbinectedin
Sensitive
:
C2
lurbinectedin
Sensitive: C2 – Inclusion Criteria
lurbinectedin
Sensitive
:
C2
PML-RARA fusion
Acute Promyelocytic Leukemia
PML-RARA fusion
Acute Promyelocytic Leukemia
tretinoin + arsenic trioxide
Sensitive: C3 – Early Trials
tretinoin + arsenic trioxide
Sensitive
:
C3
tretinoin + arsenic trioxide
Sensitive: C3 – Early Trials
tretinoin + arsenic trioxide
Sensitive
:
C3
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
pelareorep
Sensitive: C3 – Early Trials
pelareorep
Sensitive
:
C3
pelareorep
Sensitive: C3 – Early Trials
pelareorep
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
cytarabine + bortezomib + omacetaxine mepesuccinate
Sensitive: C3 – Early Trials
cytarabine + bortezomib + omacetaxine mepesuccinate
Sensitive
:
C3
cytarabine + bortezomib + omacetaxine mepesuccinate
Sensitive: C3 – Early Trials
cytarabine + bortezomib + omacetaxine mepesuccinate
Sensitive
:
C3
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
paclitaxel + pelareorep
Sensitive: C3 – Early Trials
paclitaxel + pelareorep
Sensitive
:
C3
paclitaxel + pelareorep
Sensitive: C3 – Early Trials
paclitaxel + pelareorep
Sensitive
:
C3
MGMT unmethylation
Glioblastoma
MGMT unmethylation
Glioblastoma
BAL101553
Sensitive: C3 – Early Trials
BAL101553
Sensitive
:
C3
BAL101553
Sensitive: C3 – Early Trials
BAL101553
Sensitive
:
C3
IDH2 mutation + MYC amplification + MAPRE1 overexpression
Glioblastoma
IDH2 mutation + MYC amplification + MAPRE1 overexpression
Glioblastoma
BAL101553
Sensitive: C4 – Case Studies
BAL101553
Sensitive
:
C4
BAL101553
Sensitive: C4 – Case Studies
BAL101553
Sensitive
:
C4
IDH1 mutation + MYC amplification + MAPRE1 overexpression
Glioblastoma
IDH1 mutation + MYC amplification + MAPRE1 overexpression
Glioblastoma
BAL101553
Sensitive: C4 – Case Studies
BAL101553
Sensitive
:
C4
BAL101553
Sensitive: C4 – Case Studies
BAL101553
Sensitive
:
C4
FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression
Acute Promyelocytic Leukemia
FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression
Acute Promyelocytic Leukemia
cytarabine + idarubicin hydrochloride + arsenic trioxide + hydroxyurea
Sensitive: C4 – Case Studies
cytarabine + idarubicin hydrochloride + arsenic trioxide + hydroxyurea
Sensitive
:
C4
cytarabine + idarubicin hydrochloride + arsenic trioxide + hydroxyurea
Sensitive: C4 – Case Studies
cytarabine + idarubicin hydrochloride + arsenic trioxide + hydroxyurea
Sensitive
:
C4
NUP98-RARG fusion
Acute Myelogenous Leukemia
NUP98-RARG fusion
Acute Myelogenous Leukemia
arsenic trioxide
Sensitive: C4 – Case Studies
arsenic trioxide
Sensitive
:
C4
arsenic trioxide
Sensitive: C4 – Case Studies
arsenic trioxide
Sensitive
:
C4
CLTC-ALK fusion
Diffuse Large B Cell Lymphoma
CLTC-ALK fusion
Diffuse Large B Cell Lymphoma
arsenic trioxide
Sensitive: D – Preclinical
arsenic trioxide
Sensitive
:
D
arsenic trioxide
Sensitive: D – Preclinical
arsenic trioxide
Sensitive
:
D
KRAS mutation + STK11 mutation
Non Small Cell Lung Cancer
KRAS mutation + STK11 mutation
Non Small Cell Lung Cancer
pembrolizumab + quaratusugene ozeplasmid
Sensitive: D – Preclinical
pembrolizumab + quaratusugene ozeplasmid
Sensitive
:
D
pembrolizumab + quaratusugene ozeplasmid
Sensitive: D – Preclinical
pembrolizumab + quaratusugene ozeplasmid
Sensitive
:
D
KRAS mutation
Non Small Cell Lung Cancer
KRAS mutation
Non Small Cell Lung Cancer
GZ17-6.02
Sensitive: D – Preclinical
GZ17-6.02
Sensitive
:
D
GZ17-6.02
Sensitive: D – Preclinical
GZ17-6.02
Sensitive
:
D
EGFR mutation
Non Small Cell Lung Cancer
EGFR mutation
Non Small Cell Lung Cancer
GZ17-6.02
Sensitive: D – Preclinical
GZ17-6.02
Sensitive
:
D
GZ17-6.02
Sensitive: D – Preclinical
GZ17-6.02
Sensitive
:
D
ABCG2 overexpression
Solid Tumor
ABCG2 overexpression
Solid Tumor
TP-3654 + IT-141
Sensitive: D – Preclinical
TP-3654 + IT-141
Sensitive
:
D
TP-3654 + IT-141
Sensitive: D – Preclinical
TP-3654 + IT-141
Sensitive
:
D
IDH2 mutation
Glioma
IDH2 mutation
Glioma
omacetaxine mepesuccinate
Sensitive: D – Preclinical
omacetaxine mepesuccinate
Sensitive
:
D
omacetaxine mepesuccinate
Sensitive: D – Preclinical
omacetaxine mepesuccinate
Sensitive
:
D
IDH1 mutation
Glioma
IDH1 mutation
Glioma
omacetaxine mepesuccinate
Sensitive: D – Preclinical
omacetaxine mepesuccinate
Sensitive
:
D
omacetaxine mepesuccinate
Sensitive: D – Preclinical
omacetaxine mepesuccinate
Sensitive
:
D
FLT3-ITD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation
Acute Myelogenous Leukemia
pelareorep
Sensitive: D – Preclinical
pelareorep
Sensitive
:
D
pelareorep
Sensitive: D – Preclinical
pelareorep
Sensitive
:
D
SLFN11 overexpression
Small Cell Lung Cancer
SLFN11 overexpression
Small Cell Lung Cancer
lurbinectedin
Sensitive: D – Preclinical
lurbinectedin
Sensitive
:
D
lurbinectedin
Sensitive: D – Preclinical
lurbinectedin
Sensitive
:
D
SLFN11 underexpression
Small Cell Lung Cancer
SLFN11 underexpression
Small Cell Lung Cancer
M6620 + lurbinectedin
Sensitive: D – Preclinical
M6620 + lurbinectedin
Sensitive
:
D
M6620 + lurbinectedin
Sensitive: D – Preclinical
M6620 + lurbinectedin
Sensitive
:
D
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