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BIOMARKER:

PIK3CA mutation + ER positive

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Entrez ID:

Related biomarkers:

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PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	capivasertib Sensitive: A1 - Approval capivasertib Sensitive : A1	capivasertib Sensitive: A1 - Approval capivasertib Sensitive : A1
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	GDC-0032 Sensitive: B - Late Trials GDC-0032 Sensitive : B	GDC-0032 Sensitive: B - Late Trials GDC-0032 Sensitive : B
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	alpelisib Sensitive: C3 – Early Trials alpelisib Sensitive : C3	alpelisib Sensitive: C3 – Early Trials alpelisib Sensitive : C3
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	palbociclib + GDC-0032 Sensitive: C3 – Early Trials palbociclib + GDC-0032 Sensitive : C3	palbociclib + GDC-0032 Sensitive: C3 – Early Trials palbociclib + GDC-0032 Sensitive : C3
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	palbociclib Resistant: C3 – Early Trials palbociclib Resistant : C3	palbociclib Resistant: C3 – Early Trials palbociclib Resistant : C3
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	fulvestrant Sensitive: D – Preclinical fulvestrant Sensitive : D	fulvestrant Sensitive: D – Preclinical fulvestrant Sensitive : D
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	everolimus Sensitive: D – Preclinical everolimus Sensitive : D	everolimus Sensitive: D – Preclinical everolimus Sensitive : D
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	palbociclib + alpelisib Sensitive: D – Preclinical palbociclib + alpelisib Sensitive : D	palbociclib + alpelisib Sensitive: D – Preclinical palbociclib + alpelisib Sensitive : D
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	alpelisib + ribociclib Sensitive: D – Preclinical alpelisib + ribociclib Sensitive : D	alpelisib + ribociclib Sensitive: D – Preclinical alpelisib + ribociclib Sensitive : D
PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	PIK3CA mutation + ER positive	HER2 Negative Breast Cancer	STX-478 Sensitive: D – Preclinical STX-478 Sensitive : D	STX-478 Sensitive: D – Preclinical STX-478 Sensitive : D