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BIOMARKER:

PDGFRA mutation

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Other names: Platelet Derived Growth Factor Receptor Alpha, Platelet-Derived Growth Factor Receptor Alpha Polypeptide, Alpha-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member A, CD140a Antigen, PDGF-R-Alpha, PDGFR-2, PDGFR2, Alpha Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor Alpha Receptor, PDGFR-Alpha, RHEPDGFRA, CD140A
Entrez ID:
PDGFRA mutation
GIST
ripretinib
Sensitive: B - Late Trials
PDGFRA mutation
Gastric Cancer
imatinib
Sensitive: B - Late Trials
PDGFRA mutation
GIST
avapritinib
Sensitive: C2 – Inclusion Criteria
PDGFRA mutation
GIST
imatinib
Sensitive: C2 – Inclusion Criteria
PDGFRA mutation
NSCLC
nintedanib
Sensitive: C3 – Early Trials
PDGFRA mutation
NSCLC
Immunotherapy
Sensitive: C3 – Early Trials
PDGFRA mutation
GIST
AZD1775
Sensitive: D – Preclinical
PDGFRA mutation
GIST
AZD1775 + avapritinib
Sensitive: D – Preclinical