^
Association details:
Evidence:
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Title:

Role of surgery in patients with resectable liver metastases from GISTs: a prospective, single-center, real-world study

Excerpt:
...Mutations are detected in c-kit or PDGFRα (not exon 18 D842V) using samples from biopsy or surgical specimens; 5. ...
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Title:

Imatinib TDM in GIST

Excerpt:
...- Histologically or cytologically confirmed GIST with KIT mutation or PDGFRA mutation (non-D842V)...
Trial ID:
Less C2 evidence
Evidence Level:
Resistant: C3 – Early Trials
Source:
Title:

Utility of circulating tumor DNA (ctDNA) in the management of patients with gastrointestinal stromal tumor (GIST): Analysis of 152 patients.

Published date:
05/16/2018
Excerpt:
DNA sequencing of the circulating tumor DNA (ctDNA) was perfomed on blood samples from 152 patients. 6 patients were positive for both KIT and PDGFRA mutations. There were 3 (2%) patients positive for PDGFRA D842V with resistance to imatinib.
DOI:
10.1200/JCO.2018.36.15_suppl.11539