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BIOMARKER:

PDGFRA D842V

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Other names: Platelet Derived Growth Factor Receptor Alpha, Platelet-Derived Growth Factor Receptor Alpha Polypeptide, Alpha-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member A, CD140a Antigen, PDGF-R-Alpha, PDGFR-2, PDGFR2, Alpha Platelet-Derived Growth Factor Receptor, Platelet-Derived Growth Factor Alpha Receptor, PDGFR-Alpha, RHEPDGFRA, CD140A
Entrez ID:
PDGFRA D842V
GIST
avapritinib
Sensitive: A1 - Approval
PDGFRA D842V
GIST
dasatinib
Sensitive: A2 - Guideline
PDGFRA D842V
Gastric Cancer
imatinib
Resistant: A2 - Guideline
PDGFRA D842V
GIST
ARO-002
Sensitive: C2 – Inclusion Criteria
PDGFRA D842V
GIST
sunitinib
Resistant: C3 – Early Trials
PDGFRA D842V
GIST
imatinib
Resistant: C3 – Early Trials