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BIOMARKER:
PD-L1 deletion + STK11 mutation
i
Other names:
PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule, Serine/Threonine-Protein Kinase 11, Liver Kinase B1, Serine/Threonine-Protein Kinase LKB1, Polarization-Related Protein LKB1, STK11, Serine/Threonine Kinase 11, Serine/Threonine-Protein Kinase STK11, Renal Carcinoma Antigen NY-REN-19
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Entrez ID:
29126
;
6794
Related biomarkers:
Expression
Mutation
CNA
Others
‹
STK11 mutation (33)
KRAS mutation + STK11 mutation (8)
KRAS G12C + STK11 mutation (5)
STK11 mutation + KEAP1 mutation (5)
KRAS G12D + STK11 mutation (3)
KRAS mutation + STK11 mutation + KEAP1 mutation (2)
STK11 mutation + KEAP1 mutation + KRAS G12C (2)
STK11 mutation + TP53 mutation (2)
NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)
PD-L1 rs1411262 (1)
PD-L1 rs2297136 (1)
PD-L1 rs4143815 (1)
PD-L1 rs822339 (1)
ATM S1905Ifs*25 + STK11 K262Sfs*25 (1)
EGFR wild-type + ALK wild-type + STK11 mutation (1)
KRAS G12V + STK11 mutation (1)
KRAS mutation + STK11 deletion + KEAP1 deletion (1)
KRAS mutation + STK11 mutation + TP53 mutation (1)
NFE2L2 mutation + STK11 mutation (1)
PTEN mutation + STK11 mutation (1)
STK11 D194E (1)
STK11 F354L (1)
STK11 K262Sfs*25 (1)
STK11 mutation + FAT3 mutation (1)
STK11 mutation + KEAP1 mutation + KRAS wild-type (1)
PD-L1 T290M (0)
PD-L1 mutation (0)
KEAP1 mutation + NFE2L2 mutation + STK11 mutation (0)
STK11 mutation (33)
KRAS mutation + STK11 mutation (8)
KRAS G12C + STK11 mutation (5)
STK11 mutation + KEAP1 mutation (5)
KRAS G12D + STK11 mutation (3)
KRAS mutation + STK11 mutation + KEAP1 mutation (2)
STK11 mutation + KEAP1 mutation + KRAS G12C (2)
STK11 mutation + TP53 mutation (2)
NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)
PD-L1 rs1411262 (1)
PD-L1 rs2297136 (1)
PD-L1 rs4143815 (1)
PD-L1 rs822339 (1)
ATM S1905Ifs*25 + STK11 K262Sfs*25 (1)
EGFR wild-type + ALK wild-type + STK11 mutation (1)
KRAS G12V + STK11 mutation (1)
KRAS mutation + STK11 deletion + KEAP1 deletion (1)
KRAS mutation + STK11 mutation + TP53 mutation (1)
NFE2L2 mutation + STK11 mutation (1)
PTEN mutation + STK11 mutation (1)
STK11 D194E (1)
STK11 F354L (1)
STK11 K262Sfs*25 (1)
STK11 mutation + FAT3 mutation (1)
STK11 mutation + KEAP1 mutation + KRAS wild-type (1)
PD-L1 T290M (0)
PD-L1 mutation (0)
KEAP1 mutation + NFE2L2 mutation + STK11 mutation (0)
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VERI cancer hierarchy
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PD-L1 deletion + STK11 mutation
Non Small Cell Lung Cancer
PD-L1 deletion + STK11 mutation
Non Small Cell Lung Cancer
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
Immunotherapy
Resistant: C3 – Early Trials
Immunotherapy
Resistant
:
C3
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