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BIOMARKER:

PAK4 deletion

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Other names: PAK4, P21 (RAC1) Activated Kinase 4, P21 Protein (Cdc42/Rac)-Activated Kinase 4, Serine/Threonine-Protein Kinase PAK 4, P21(CDKN1A)-Activated Kinase 4, Protein Kinase Related To S. Cerevisiae STE20, Effector For Cdc42Hs, P21-Activated Kinase 4
Entrez ID:
Related biomarkers:
PAK4 deletion
B Acute Lymphoblastic Leukemia
blinatumomab
Sensitive: C3 – Early Trials
PAK4 deletion
HCC
Immunotherapy
Sensitive: C3 – Early Trials
PAK4 deletion
ALL
blinatumomab
Sensitive: C3 – Early Trials
PAK4 deletion
Prolymphocytic Leukemia
alemtuzumab
Resistant: C4 – Case Studies
PAK4 deletion
Estrogen Receptor Positive Breast Cancer
ribociclib + SNS-510
Sensitive: D – Preclinical
PAK4 deletion
Estrogen Receptor Positive Breast Cancer
palbociclib + SNS-510
Sensitive: D – Preclinical
PAK4 deletion
Ewing Sarcoma
ASP7487
Sensitive: D – Preclinical
PAK4 deletion
Ewing Sarcoma
palbociclib
Sensitive: D – Preclinical
PAK4 deletion
Solid Tumor
PD1 inhibitor
Resistant: D – Preclinical