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DRUG:

Onureg (azacitidine oral)

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Company:

BMS

Drug class:

DNMT inhibitor

Related drugs:

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decitabine (40)

decitabine/cedazuridine (10)

decitabine (40)

decitabine/cedazuridine (10)

›

No biomarker	Acute Myelogenous Leukemia	No biomarker	Acute Myelogenous Leukemia	azacitidine oral Sensitive: A1 - Approval azacitidine oral Sensitive : A1	azacitidine oral Sensitive: A1 - Approval azacitidine oral Sensitive : A1
BCL2 overexpression	Diffuse Large B Cell Lymphoma	BCL2 overexpression	Diffuse Large B Cell Lymphoma	azacitidine oral Sensitive: C3 – Early Trials azacitidine oral Sensitive : C3	azacitidine oral Sensitive: C3 – Early Trials azacitidine oral Sensitive : C3
MYC overexpression + BCL2 overexpression	Diffuse Large B Cell Lymphoma	MYC overexpression + BCL2 overexpression	Diffuse Large B Cell Lymphoma	azacitidine oral Sensitive: C3 – Early Trials azacitidine oral Sensitive : C3	azacitidine oral Sensitive: C3 – Early Trials azacitidine oral Sensitive : C3
MYC overexpression	Diffuse Large B Cell Lymphoma	MYC overexpression	Diffuse Large B Cell Lymphoma	azacitidine oral Sensitive: C3 – Early Trials azacitidine oral Sensitive : C3	azacitidine oral Sensitive: C3 – Early Trials azacitidine oral Sensitive : C3
DNMT3A mutation	Peripheral T-cell Lymphoma	DNMT3A mutation	Peripheral T-cell Lymphoma	CHOP + azacitidine oral Resistant: C3 – Early Trials CHOP + azacitidine oral Resistant : C3	CHOP + azacitidine oral Resistant: C3 – Early Trials CHOP + azacitidine oral Resistant : C3
TET2 mutation	Peripheral T-cell Lymphoma	TET2 mutation	Peripheral T-cell Lymphoma	CHOP + azacitidine oral Sensitive: C3 – Early Trials CHOP + azacitidine oral Sensitive : C3	CHOP + azacitidine oral Sensitive: C3 – Early Trials CHOP + azacitidine oral Sensitive : C3
ITGAM expression	Acute Myelogenous Leukemia	ITGAM expression	Acute Myelogenous Leukemia	azacitidine oral Sensitive: D – Preclinical azacitidine oral Sensitive : D	azacitidine oral Sensitive: D – Preclinical azacitidine oral Sensitive : D