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BIOMARKER:

NRG1 overexpression

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Entrez ID:

Related biomarkers:

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NRG1 mutation (3)

NRG1 rearrangement (1)

NRG1 mutation (3)

NRG1 rearrangement (1)

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NRG1 overexpression	Esophageal Squamous Cell Carcinoma	NRG1 overexpression	Esophageal Squamous Cell Carcinoma	AV-203 Sensitive: C3 – Early Trials AV-203 Sensitive : C3	AV-203 Sensitive: C3 – Early Trials AV-203 Sensitive : C3
NRG1 overexpression	Non Small Cell Lung Cancer	NRG1 overexpression	Non Small Cell Lung Cancer	U3-1287 Sensitive: C3 – Early Trials U3-1287 Sensitive : C3	U3-1287 Sensitive: C3 – Early Trials U3-1287 Sensitive : C3
NRG1 overexpression	HER2 Positive Breast Cancer	NRG1 overexpression	HER2 Positive Breast Cancer	trastuzumab + pertuzumab Sensitive: C3 – Early Trials trastuzumab + pertuzumab Sensitive : C3	trastuzumab + pertuzumab Sensitive: C3 – Early Trials trastuzumab + pertuzumab Sensitive : C3
NRG1 overexpression	Head and Neck Cancer	NRG1 overexpression	Head and Neck Cancer	cetuximab Resistant: D – Preclinical cetuximab Resistant : D	cetuximab Resistant: D – Preclinical cetuximab Resistant : D